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Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup.
J Urol. 1999 Nov; 162(5):1640-4.JU

Abstract

PURPOSE

The high-powered holmium:YAG laser can be used for incision, ablation and resection of the prostate. The technique of holmium laser resection of the prostate is compared to transurethral prostatic resection for surgical management of benign prostatic hyperplasia in this prospective randomized study.

MATERIALS AND METHODS

A total of 120 urodynamically obstructed cases were randomized to holmium laser or transurethral prostatic resection. All eligible patients were assessed preoperatively and at 3 weeks, and 3, 6 and 12 months postoperatively with an American Urological Association symptom score, peak urinary flow rate, and questionnaires concerning sexual function and continence. Preoperative pressure flow study, ultrasound prostate volume assessment and post-void residual volume measurement were repeated at the 6-month visit. All complications were noted.

RESULTS

Holmium laser and transurethral resections resulted in significant improvements in symptom score, quality of life score, peak urinary flow rate and post-void residual urine measurements. Operating time was significantly longer in the holmium group but nursing contact time, catheter time and hospital stay were significantly less compared to the transurethral prostatic resection group. Urodynamic results were equivalent at 6 months. There were fewer side effects in the holmium group. Effects on continence, potency and symptoms were similar with 1-year followup.

CONCLUSIONS

Holmium and transurethral resections of the prostate appear to be equivalent in surgical management of bladder outflow obstruction due to benign prostate hyperplasia. Perioperative morbidity was less in the holmium group.

Authors+Show Affiliations

Urology Department, Tauranga Hospital, New Zealand.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10524887

Citation

Gilling, P J., et al. "Holmium Laser Versus Transurethral Resection of the Prostate: a Randomized Prospective Trial With 1-year Followup." The Journal of Urology, vol. 162, no. 5, 1999, pp. 1640-4.
Gilling PJ, Mackey M, Cresswell M, et al. Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup. J Urol. 1999;162(5):1640-4.
Gilling, P. J., Mackey, M., Cresswell, M., Kennett, K., Kabalin, J. N., & Fraundorfer, M. R. (1999). Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup. The Journal of Urology, 162(5), 1640-4.
Gilling PJ, et al. Holmium Laser Versus Transurethral Resection of the Prostate: a Randomized Prospective Trial With 1-year Followup. J Urol. 1999;162(5):1640-4. PubMed PMID: 10524887.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup. AU - Gilling,P J, AU - Mackey,M, AU - Cresswell,M, AU - Kennett,K, AU - Kabalin,J N, AU - Fraundorfer,M R, PY - 1999/10/19/pubmed PY - 1999/10/19/medline PY - 1999/10/19/entrez SP - 1640 EP - 4 JF - The Journal of urology JO - J Urol VL - 162 IS - 5 N2 - PURPOSE: The high-powered holmium:YAG laser can be used for incision, ablation and resection of the prostate. The technique of holmium laser resection of the prostate is compared to transurethral prostatic resection for surgical management of benign prostatic hyperplasia in this prospective randomized study. MATERIALS AND METHODS: A total of 120 urodynamically obstructed cases were randomized to holmium laser or transurethral prostatic resection. All eligible patients were assessed preoperatively and at 3 weeks, and 3, 6 and 12 months postoperatively with an American Urological Association symptom score, peak urinary flow rate, and questionnaires concerning sexual function and continence. Preoperative pressure flow study, ultrasound prostate volume assessment and post-void residual volume measurement were repeated at the 6-month visit. All complications were noted. RESULTS: Holmium laser and transurethral resections resulted in significant improvements in symptom score, quality of life score, peak urinary flow rate and post-void residual urine measurements. Operating time was significantly longer in the holmium group but nursing contact time, catheter time and hospital stay were significantly less compared to the transurethral prostatic resection group. Urodynamic results were equivalent at 6 months. There were fewer side effects in the holmium group. Effects on continence, potency and symptoms were similar with 1-year followup. CONCLUSIONS: Holmium and transurethral resections of the prostate appear to be equivalent in surgical management of bladder outflow obstruction due to benign prostate hyperplasia. Perioperative morbidity was less in the holmium group. SN - 0022-5347 UR - https://www.unboundmedicine.com/medline/citation/10524887/Holmium_laser_versus_transurethral_resection_of_the_prostate:_a_randomized_prospective_trial_with_1_year_followup_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-5347(05)68186-4 DB - PRIME DP - Unbound Medicine ER -