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Comparison of bispectral EEG analysis and auditory evoked potentials for monitoring depth of anaesthesia during propofol anaesthesia.
Br J Anaesth. 1999 May; 82(5):672-8.BJ

Abstract

We have compared the auditory evoked potential index (AEPIndex) and bispectral index (BIS) for monitoring depth of anaesthesia in spontaneously breathing surgical patients. Twenty patients (aged 17-49 yr) undergoing day surgery were anaesthetized with computer-controlled infusions of propofol. The mean (SD and range) of each measurement was determined during consciousness and unconsciousness and at specific times during the perioperative period. Mean values for AEPIndex during consciousness and unconsciousness were 74.5 (SD 14.7) 36.7 (7.1), respectively. BIS had mean values of 89.5 (SD 4.6) during consciousness and 48.8 (16.4) during unconsciousness. AEPIndex and BIS were greater during consciousness compared with during unconsciousness. The average awake values of AEPIndex were significantly higher than all average values during unconsciousness but this was not the case for BIS. BIS increased gradually during emergence from anaesthesia and may therefore be able to predict recovery of consciousness at the end of anaesthesia. AEPIndex was more able to detect the transition from unconsciousness to consciousness.

Authors+Show Affiliations

Department of Anaesthesia, General Infirmary at Leeds, UK.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

10536541

Citation

Gajraj, R J., et al. "Comparison of Bispectral EEG Analysis and Auditory Evoked Potentials for Monitoring Depth of Anaesthesia During Propofol Anaesthesia." British Journal of Anaesthesia, vol. 82, no. 5, 1999, pp. 672-8.
Gajraj RJ, Doi M, Mantzaridis H, et al. Comparison of bispectral EEG analysis and auditory evoked potentials for monitoring depth of anaesthesia during propofol anaesthesia. Br J Anaesth. 1999;82(5):672-8.
Gajraj, R. J., Doi, M., Mantzaridis, H., & Kenny, G. N. (1999). Comparison of bispectral EEG analysis and auditory evoked potentials for monitoring depth of anaesthesia during propofol anaesthesia. British Journal of Anaesthesia, 82(5), 672-8.
Gajraj RJ, et al. Comparison of Bispectral EEG Analysis and Auditory Evoked Potentials for Monitoring Depth of Anaesthesia During Propofol Anaesthesia. Br J Anaesth. 1999;82(5):672-8. PubMed PMID: 10536541.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of bispectral EEG analysis and auditory evoked potentials for monitoring depth of anaesthesia during propofol anaesthesia. AU - Gajraj,R J, AU - Doi,M, AU - Mantzaridis,H, AU - Kenny,G N, PY - 1999/10/28/pubmed PY - 1999/10/28/medline PY - 1999/10/28/entrez SP - 672 EP - 8 JF - British journal of anaesthesia JO - Br J Anaesth VL - 82 IS - 5 N2 - We have compared the auditory evoked potential index (AEPIndex) and bispectral index (BIS) for monitoring depth of anaesthesia in spontaneously breathing surgical patients. Twenty patients (aged 17-49 yr) undergoing day surgery were anaesthetized with computer-controlled infusions of propofol. The mean (SD and range) of each measurement was determined during consciousness and unconsciousness and at specific times during the perioperative period. Mean values for AEPIndex during consciousness and unconsciousness were 74.5 (SD 14.7) 36.7 (7.1), respectively. BIS had mean values of 89.5 (SD 4.6) during consciousness and 48.8 (16.4) during unconsciousness. AEPIndex and BIS were greater during consciousness compared with during unconsciousness. The average awake values of AEPIndex were significantly higher than all average values during unconsciousness but this was not the case for BIS. BIS increased gradually during emergence from anaesthesia and may therefore be able to predict recovery of consciousness at the end of anaesthesia. AEPIndex was more able to detect the transition from unconsciousness to consciousness. SN - 0007-0912 UR - https://www.unboundmedicine.com/medline/citation/10536541/Comparison_of_bispectral_EEG_analysis_and_auditory_evoked_potentials_for_monitoring_depth_of_anaesthesia_during_propofol_anaesthesia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0007-0912(17)38520-3 DB - PRIME DP - Unbound Medicine ER -