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In vitro susceptibilities of Burkholderia mallei in comparison to those of other pathogenic Burkholderia spp.
Antimicrob Agents Chemother. 1999 Nov; 43(11):2773-5.AA

Abstract

The in vitro antimicrobial susceptibilities of isolates of Burkholderia mallei to 16 antibiotics were assessed and compared with the susceptibilities of Burkholderia pseudomallei and Burkholderia cepacia. The antibiotic susceptibility profile of B. mallei resembled that of B. pseudomallei more closely than that of B. cepacia, which corresponds to their similarities in terms of biochemistry, antigenicity, and pathogenicity. Ceftazidime, imipenem, doxycycline, and ciprofloxacin were active against both B. mallei and B. pseudomallei. Gentamicin was active against B. mallei but not against B. pseudomallei. Antibiotics clinically proven to be effective in the treatment of melioidosis may therefore be effective for treating glanders.

Authors+Show Affiliations

CBD Porton Down, Salisbury, Wilts SP4 OJQ, United Kingdom.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10543761

Citation

Kenny, D J., et al. "In Vitro Susceptibilities of Burkholderia Mallei in Comparison to Those of Other Pathogenic Burkholderia Spp." Antimicrobial Agents and Chemotherapy, vol. 43, no. 11, 1999, pp. 2773-5.
Kenny DJ, Russell P, Rogers D, et al. In vitro susceptibilities of Burkholderia mallei in comparison to those of other pathogenic Burkholderia spp. Antimicrob Agents Chemother. 1999;43(11):2773-5.
Kenny, D. J., Russell, P., Rogers, D., Eley, S. M., & Titball, R. W. (1999). In vitro susceptibilities of Burkholderia mallei in comparison to those of other pathogenic Burkholderia spp. Antimicrobial Agents and Chemotherapy, 43(11), 2773-5.
Kenny DJ, et al. In Vitro Susceptibilities of Burkholderia Mallei in Comparison to Those of Other Pathogenic Burkholderia Spp. Antimicrob Agents Chemother. 1999;43(11):2773-5. PubMed PMID: 10543761.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro susceptibilities of Burkholderia mallei in comparison to those of other pathogenic Burkholderia spp. AU - Kenny,D J, AU - Russell,P, AU - Rogers,D, AU - Eley,S M, AU - Titball,R W, PY - 1999/10/30/pubmed PY - 1999/10/30/medline PY - 1999/10/30/entrez SP - 2773 EP - 5 JF - Antimicrobial agents and chemotherapy JO - Antimicrob Agents Chemother VL - 43 IS - 11 N2 - The in vitro antimicrobial susceptibilities of isolates of Burkholderia mallei to 16 antibiotics were assessed and compared with the susceptibilities of Burkholderia pseudomallei and Burkholderia cepacia. The antibiotic susceptibility profile of B. mallei resembled that of B. pseudomallei more closely than that of B. cepacia, which corresponds to their similarities in terms of biochemistry, antigenicity, and pathogenicity. Ceftazidime, imipenem, doxycycline, and ciprofloxacin were active against both B. mallei and B. pseudomallei. Gentamicin was active against B. mallei but not against B. pseudomallei. Antibiotics clinically proven to be effective in the treatment of melioidosis may therefore be effective for treating glanders. SN - 0066-4804 UR - https://www.unboundmedicine.com/medline/citation/10543761/In_vitro_susceptibilities_of_Burkholderia_mallei_in_comparison_to_those_of_other_pathogenic_Burkholderia_spp_ L2 - http://aac.asm.org/cgi/pmidlookup?view=long&pmid=10543761 DB - PRIME DP - Unbound Medicine ER -