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Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand.
Antimicrob Agents Chemother. 1999 Nov; 43(11):2817-8.AA

Abstract

Azithromycin was given to mice and humans infected with strains of Orientia tsutsugamushi from northern Thailand, where drug-resistant scrub typhus occurs. Azithromycin and doxycycline yielded comparable mouse survival rates (73 and 79%, respectively; P > 0.5). Symptoms, signs, and fever in two pregnant women abated rapidly with azithromycin. Prospective human trials are needed.

Authors+Show Affiliations

Department of Retrovirology, U.S. Army Component, Bangkok, Thailand. LTC-George_Watt@WRSMTP.CCMAIL.ARMY.MILNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

10543774

Citation

Watt, G, et al. "Azithromycin Activities Against Orientia Tsutsugamushi Strains Isolated in Cases of Scrub Typhus in Northern Thailand." Antimicrobial Agents and Chemotherapy, vol. 43, no. 11, 1999, pp. 2817-8.
Watt G, Kantipong P, Jongsakul K, et al. Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand. Antimicrob Agents Chemother. 1999;43(11):2817-8.
Watt, G., Kantipong, P., Jongsakul, K., Watcharapichat, P., & Phulsuksombati, D. (1999). Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand. Antimicrobial Agents and Chemotherapy, 43(11), 2817-8.
Watt G, et al. Azithromycin Activities Against Orientia Tsutsugamushi Strains Isolated in Cases of Scrub Typhus in Northern Thailand. Antimicrob Agents Chemother. 1999;43(11):2817-8. PubMed PMID: 10543774.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand. AU - Watt,G, AU - Kantipong,P, AU - Jongsakul,K, AU - Watcharapichat,P, AU - Phulsuksombati,D, PY - 1999/11/5/pubmed PY - 1999/11/5/medline PY - 1999/11/5/entrez SP - 2817 EP - 8 JF - Antimicrobial agents and chemotherapy JO - Antimicrob Agents Chemother VL - 43 IS - 11 N2 - Azithromycin was given to mice and humans infected with strains of Orientia tsutsugamushi from northern Thailand, where drug-resistant scrub typhus occurs. Azithromycin and doxycycline yielded comparable mouse survival rates (73 and 79%, respectively; P > 0.5). Symptoms, signs, and fever in two pregnant women abated rapidly with azithromycin. Prospective human trials are needed. SN - 0066-4804 UR - https://www.unboundmedicine.com/medline/citation/10543774/Azithromycin_activities_against_Orientia_tsutsugamushi_strains_isolated_in_cases_of_scrub_typhus_in_Northern_Thailand_ L2 - http://aac.asm.org/cgi/pmidlookup?view=long&pmid=10543774 DB - PRIME DP - Unbound Medicine ER -