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Giant viruses infecting algae.
Annu Rev Microbiol. 1999; 53:447-94.AR

Abstract

Paramecium bursaria chlorella virus (PBCV-1) is the prototype of a family of large, icosahedral, plaque-forming, double-stranded-DNA-containing viruses that replicate in certain unicellular, eukaryotic chlorella-like green algae. DNA sequence analysis of its 330, 742-bp genome leads to the prediction that this phycodnavirus has 376 protein-encoding genes and 10 transfer RNA genes. The predicted gene products of approximately 40% of these genes resemble proteins of known function. The chlorella viruses have other features that distinguish them from most viruses, in addition to their large genome size. These features include the following: (a) The viruses encode multiple DNA methyltransferases and DNA site-specific endonucleases; (b) PBCV-1 encodes at least part, if not the entire machinery to glycosylate its proteins; (c) PBCV-1 has at least two types of introns--a self-splicing intron in a transcription factor-like gene and a splicesomal processed type of intron in its DNA polymerase gene. Unlike the chlorella viruses, large double-stranded-DNA-containing viruses that infect marine, filamentous brown algae have a circular genome and a lysogenic phase in their life cycle.

Authors+Show Affiliations

Department of Plant Pathology, University of Nebraska, Lincoln 68583-0722, USA. jvanetten@unlnotes.unl.eduNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

10547698

Citation

Van Etten, J L., and R H. Meints. "Giant Viruses Infecting Algae." Annual Review of Microbiology, vol. 53, 1999, pp. 447-94.
Van Etten JL, Meints RH. Giant viruses infecting algae. Annu Rev Microbiol. 1999;53:447-94.
Van Etten, J. L., & Meints, R. H. (1999). Giant viruses infecting algae. Annual Review of Microbiology, 53, 447-94.
Van Etten JL, Meints RH. Giant Viruses Infecting Algae. Annu Rev Microbiol. 1999;53:447-94. PubMed PMID: 10547698.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Giant viruses infecting algae. AU - Van Etten,J L, AU - Meints,R H, PY - 1999/11/5/pubmed PY - 1999/11/5/medline PY - 1999/11/5/entrez SP - 447 EP - 94 JF - Annual review of microbiology JO - Annu Rev Microbiol VL - 53 N2 - Paramecium bursaria chlorella virus (PBCV-1) is the prototype of a family of large, icosahedral, plaque-forming, double-stranded-DNA-containing viruses that replicate in certain unicellular, eukaryotic chlorella-like green algae. DNA sequence analysis of its 330, 742-bp genome leads to the prediction that this phycodnavirus has 376 protein-encoding genes and 10 transfer RNA genes. The predicted gene products of approximately 40% of these genes resemble proteins of known function. The chlorella viruses have other features that distinguish them from most viruses, in addition to their large genome size. These features include the following: (a) The viruses encode multiple DNA methyltransferases and DNA site-specific endonucleases; (b) PBCV-1 encodes at least part, if not the entire machinery to glycosylate its proteins; (c) PBCV-1 has at least two types of introns--a self-splicing intron in a transcription factor-like gene and a splicesomal processed type of intron in its DNA polymerase gene. Unlike the chlorella viruses, large double-stranded-DNA-containing viruses that infect marine, filamentous brown algae have a circular genome and a lysogenic phase in their life cycle. SN - 0066-4227 UR - https://www.unboundmedicine.com/medline/citation/10547698/Giant_viruses_infecting_algae_ L2 - https://arjournals.annualreviews.org/doi/10.1146/annurev.micro.53.1.447?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -