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Comparison of 9 mg of intrathecal plain and hyperbaric bupivacaine both with fentanyl for cesarean delivery.
Anesth Analg. 1999 Nov; 89(5):1257-62.A&A

Abstract

We randomized 76 parturients to a double-blinded trial to receive spinal anesthesia with either hyperbaric or plain bupivacaine 9 mg with fentanyl 20 microg for elective cesarean delivery. A combined spinal-epidural technique was used. The onset and duration of anesthesia (absence of pinprick sensation), analgesia (absence of sharp sensation to pinprick), and absence of cold sensation and motor block were measured until recovery from the motor block. No major differences were seen in onset or duration of anesthesia between the groups. Motor block, however, vanished faster when hyperbaric bupivacaine was used (P < 0.05). The level of anesthesia (no pinprick sensation) required for painless operation was at dermatome T5. At this time, the absence of cold sensation ranged from dermatome T1 to C3. The median time for the anesthesia to reach dermatome T5 was 10 min. Cervical spread of pinprick anesthesia was noted in six patients, and five needed supplementary analgesics during surgery (not significant between the groups). Maternal satisfaction was good. Nine milligrams of either plain or hyperbaric bupivacaine with fentanyl intrathecally provided similar onset, depth, and duration of sensory anesthesia for cesarean delivery with good maternal satisfaction. Motor block developed and diminished faster with the hyperbaric solution.

IMPLICATIONS

Nine milligrams of either plain or hyperbaric bupivacaine with fentanyl intrathecally provided similar onset, depth, and duration of sensory anesthesia for cesarean delivery with good maternal satisfaction. Motor block developed and diminished faster with the hyperbaric solution.

Authors+Show Affiliations

Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Finland. johanna.sarvela@huch.fiNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

10553846

Citation

Sarvela, P J., et al. "Comparison of 9 Mg of Intrathecal Plain and Hyperbaric Bupivacaine Both With Fentanyl for Cesarean Delivery." Anesthesia and Analgesia, vol. 89, no. 5, 1999, pp. 1257-62.
Sarvela PJ, Halonen PM, Korttila KT. Comparison of 9 mg of intrathecal plain and hyperbaric bupivacaine both with fentanyl for cesarean delivery. Anesth Analg. 1999;89(5):1257-62.
Sarvela, P. J., Halonen, P. M., & Korttila, K. T. (1999). Comparison of 9 mg of intrathecal plain and hyperbaric bupivacaine both with fentanyl for cesarean delivery. Anesthesia and Analgesia, 89(5), 1257-62.
Sarvela PJ, Halonen PM, Korttila KT. Comparison of 9 Mg of Intrathecal Plain and Hyperbaric Bupivacaine Both With Fentanyl for Cesarean Delivery. Anesth Analg. 1999;89(5):1257-62. PubMed PMID: 10553846.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of 9 mg of intrathecal plain and hyperbaric bupivacaine both with fentanyl for cesarean delivery. AU - Sarvela,P J, AU - Halonen,P M, AU - Korttila,K T, PY - 1999/11/30/pubmed PY - 1999/11/30/medline PY - 1999/11/30/entrez SP - 1257 EP - 62 JF - Anesthesia and analgesia JO - Anesth Analg VL - 89 IS - 5 N2 - UNLABELLED: We randomized 76 parturients to a double-blinded trial to receive spinal anesthesia with either hyperbaric or plain bupivacaine 9 mg with fentanyl 20 microg for elective cesarean delivery. A combined spinal-epidural technique was used. The onset and duration of anesthesia (absence of pinprick sensation), analgesia (absence of sharp sensation to pinprick), and absence of cold sensation and motor block were measured until recovery from the motor block. No major differences were seen in onset or duration of anesthesia between the groups. Motor block, however, vanished faster when hyperbaric bupivacaine was used (P < 0.05). The level of anesthesia (no pinprick sensation) required for painless operation was at dermatome T5. At this time, the absence of cold sensation ranged from dermatome T1 to C3. The median time for the anesthesia to reach dermatome T5 was 10 min. Cervical spread of pinprick anesthesia was noted in six patients, and five needed supplementary analgesics during surgery (not significant between the groups). Maternal satisfaction was good. Nine milligrams of either plain or hyperbaric bupivacaine with fentanyl intrathecally provided similar onset, depth, and duration of sensory anesthesia for cesarean delivery with good maternal satisfaction. Motor block developed and diminished faster with the hyperbaric solution. IMPLICATIONS: Nine milligrams of either plain or hyperbaric bupivacaine with fentanyl intrathecally provided similar onset, depth, and duration of sensory anesthesia for cesarean delivery with good maternal satisfaction. Motor block developed and diminished faster with the hyperbaric solution. SN - 0003-2999 UR - https://www.unboundmedicine.com/medline/citation/10553846/Comparison_of_9_mg_of_intrathecal_plain_and_hyperbaric_bupivacaine_both_with_fentanyl_for_cesarean_delivery_ L2 - https://Insights.ovid.com/pubmed?pmid=10553846 DB - PRIME DP - Unbound Medicine ER -