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Sequential changes in bronchoalveolar lavage cells and cytokines in a patient progressing from acute to chronic bird Fancier's lung disease.
Intern Med. 1999 Nov; 38(11):896-9.IM

Abstract

A 65-year-old pigeon breeder who presented with acute hypersensitivity pneumonitis refused to give up contact with pigeons and her lung disease, which had initially improved in hospital in response to removal from pigeons, progressed to chronic interstitial fibrosis. Bronchoalveolar lavage lymphocytes fell from 50.0% of total cells in December 1986 to 27.1% in February 1990. The ratio of CD4+/CD8+ lymphocytes shifted from 0.43 to 1.47. Furthermore, IL-6 and TNF-alpha were elevated initially and were much higher at the second time point. These data pointed to the importance of CD4+ lymphocytes, IL-6 and TNF-alpha in the development of pulmonary fibrosis.

Authors+Show Affiliations

Pulmonary Medicine, Tokyo Medical and Dental University.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10563753

Citation

Ohtani, Y, et al. "Sequential Changes in Bronchoalveolar Lavage Cells and Cytokines in a Patient Progressing From Acute to Chronic Bird Fancier's Lung Disease." Internal Medicine (Tokyo, Japan), vol. 38, no. 11, 1999, pp. 896-9.
Ohtani Y, Hisauchi K, Sumi Y, et al. Sequential changes in bronchoalveolar lavage cells and cytokines in a patient progressing from acute to chronic bird Fancier's lung disease. Intern Med. 1999;38(11):896-9.
Ohtani, Y., Hisauchi, K., Sumi, Y., Miyashita, Y., Sawada, M., Miyake, S., & Yoshizawa, Y. (1999). Sequential changes in bronchoalveolar lavage cells and cytokines in a patient progressing from acute to chronic bird Fancier's lung disease. Internal Medicine (Tokyo, Japan), 38(11), 896-9.
Ohtani Y, et al. Sequential Changes in Bronchoalveolar Lavage Cells and Cytokines in a Patient Progressing From Acute to Chronic Bird Fancier's Lung Disease. Intern Med. 1999;38(11):896-9. PubMed PMID: 10563753.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sequential changes in bronchoalveolar lavage cells and cytokines in a patient progressing from acute to chronic bird Fancier's lung disease. AU - Ohtani,Y, AU - Hisauchi,K, AU - Sumi,Y, AU - Miyashita,Y, AU - Sawada,M, AU - Miyake,S, AU - Yoshizawa,Y, PY - 1999/11/24/pubmed PY - 1999/11/24/medline PY - 1999/11/24/entrez SP - 896 EP - 9 JF - Internal medicine (Tokyo, Japan) JO - Intern Med VL - 38 IS - 11 N2 - A 65-year-old pigeon breeder who presented with acute hypersensitivity pneumonitis refused to give up contact with pigeons and her lung disease, which had initially improved in hospital in response to removal from pigeons, progressed to chronic interstitial fibrosis. Bronchoalveolar lavage lymphocytes fell from 50.0% of total cells in December 1986 to 27.1% in February 1990. The ratio of CD4+/CD8+ lymphocytes shifted from 0.43 to 1.47. Furthermore, IL-6 and TNF-alpha were elevated initially and were much higher at the second time point. These data pointed to the importance of CD4+ lymphocytes, IL-6 and TNF-alpha in the development of pulmonary fibrosis. SN - 0918-2918 UR - https://www.unboundmedicine.com/medline/citation/10563753/Sequential_changes_in_bronchoalveolar_lavage_cells_and_cytokines_in_a_patient_progressing_from_acute_to_chronic_bird_Fancier's_lung_disease_ L2 - https://joi.jlc.jst.go.jp/JST.Journalarchive/internalmedicine1992/38.896?from=PubMed DB - PRIME DP - Unbound Medicine ER -