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Clinical value of symptom assessment in patients with constipation.
Dis Colon Rectum 1999; 42(11):1401-8; discussion 1408-10DC

Abstract

PURPOSE

This study was designed to evaluate symptoms and clinical findings in a prospective series of patients with chronic constipation.

METHODS

A total of 155 consecutive patients with intractable constipation underwent detailed symptom registration, anorectal manometry, electromyography, colonic transit time measurement, and defecography.

RESULTS

All investigations were completed by 134 patients (112 females) with a median age of 52 (range, 17-79) years. Whole-gut transit time was delayed in 55 patients (41 percent), pelvic floor dysfunction was diagnosed in 59 patients (44 percent), but in 35 percent of patients both transit time and pelvic floor function were found to be normal. Three symptoms were shown to have an independent value for the diagnosis of slow-transit constipation. Patients with slow transit more often reported two or fewer stools per week (84 vs. 46 percent), laxative dependence (87 vs. 44 percent), and a history of constipation since childhood (58 vs. 22 percent) than did those with normal transit. Pelvic floor dysfunction was associated with a higher prevalence of backache (53 vs. 33 percent) and a lower prevalence of normal stool frequency (19 vs. 36 percent), heartburn (12 vs. 27 percent), and a history of anorectal surgery (7 vs. 21 percent) compared with those with normal pelvic floor function. All four symptoms retained an independent value in the logistic regression analysis for pelvic floor dysfunction. Two symptoms characterized the group with normal transit and normal pelvic floor function: normal stool frequency and alternating diarrhea and constipation.

CONCLUSIONS

Symptoms are good predictors of transit time but poorer predictors of pelvic floor function in patients with constipation.

Authors+Show Affiliations

Department of Surgery, Karolinska Institutet, Huddinge University Hospital, Sweden.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

10566527

Citation

Glia, A, et al. "Clinical Value of Symptom Assessment in Patients With Constipation." Diseases of the Colon and Rectum, vol. 42, no. 11, 1999, pp. 1401-8; discussion 1408-10.
Glia A, Lindberg G, Nilsson LH, et al. Clinical value of symptom assessment in patients with constipation. Dis Colon Rectum. 1999;42(11):1401-8; discussion 1408-10.
Glia, A., Lindberg, G., Nilsson, L. H., Mihocsa, L., & Akerlund, J. E. (1999). Clinical value of symptom assessment in patients with constipation. Diseases of the Colon and Rectum, 42(11), pp. 1401-8; discussion 1408-10.
Glia A, et al. Clinical Value of Symptom Assessment in Patients With Constipation. Dis Colon Rectum. 1999;42(11):1401-8; discussion 1408-10. PubMed PMID: 10566527.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical value of symptom assessment in patients with constipation. AU - Glia,A, AU - Lindberg,G, AU - Nilsson,L H, AU - Mihocsa,L, AU - Akerlund,J E, PY - 1999/11/24/pubmed PY - 1999/11/24/medline PY - 1999/11/24/entrez SP - 1401-8; discussion 1408-10 JF - Diseases of the colon and rectum JO - Dis. Colon Rectum VL - 42 IS - 11 N2 - PURPOSE: This study was designed to evaluate symptoms and clinical findings in a prospective series of patients with chronic constipation. METHODS: A total of 155 consecutive patients with intractable constipation underwent detailed symptom registration, anorectal manometry, electromyography, colonic transit time measurement, and defecography. RESULTS: All investigations were completed by 134 patients (112 females) with a median age of 52 (range, 17-79) years. Whole-gut transit time was delayed in 55 patients (41 percent), pelvic floor dysfunction was diagnosed in 59 patients (44 percent), but in 35 percent of patients both transit time and pelvic floor function were found to be normal. Three symptoms were shown to have an independent value for the diagnosis of slow-transit constipation. Patients with slow transit more often reported two or fewer stools per week (84 vs. 46 percent), laxative dependence (87 vs. 44 percent), and a history of constipation since childhood (58 vs. 22 percent) than did those with normal transit. Pelvic floor dysfunction was associated with a higher prevalence of backache (53 vs. 33 percent) and a lower prevalence of normal stool frequency (19 vs. 36 percent), heartburn (12 vs. 27 percent), and a history of anorectal surgery (7 vs. 21 percent) compared with those with normal pelvic floor function. All four symptoms retained an independent value in the logistic regression analysis for pelvic floor dysfunction. Two symptoms characterized the group with normal transit and normal pelvic floor function: normal stool frequency and alternating diarrhea and constipation. CONCLUSIONS: Symptoms are good predictors of transit time but poorer predictors of pelvic floor function in patients with constipation. SN - 0012-3706 UR - https://www.unboundmedicine.com/medline/citation/10566527/Clinical_value_of_symptom_assessment_in_patients_with_constipation_ L2 - http://link.springer.com/article/10.1007/bf02235036 DB - PRIME DP - Unbound Medicine ER -