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[Morphology of the optic papilla in glaucoma. II. Secondary chronic open angle glaucoma].
Klin Monbl Augenheilkd. 1999 Oct; 215(4):221-7.KM

Abstract

Previous studies have shown that the chronic open-angle glaucomas form a heterogeneous spectrum of diseases which have in common an open anterior chamber angle and glaucomatous optic nerve damage. Purpose of this study was to evaluate whether the appearance of the optic disc shows specific features among various types of secondary chronic open-angle glaucoma.

METHODS

Clinical data and color-stereo optic disc photographs of 126 patients with pseudoexfoliative glaucoma and 47 patients with pigmentary glaucoma were compared with those of 501 patients with primary open-angle glaucoma (POAG) and of 481 normal subjects. The glaucoma groups did not differ in neuroretinal rim nor in perimetric mean defect.

RESULTS

Mean optic disc area was significantly smaller in the pseudoexfoliative glaucoma eyes (2.54 +/- 0.51 mm2 vs. 2.71 +/- 0.63 mm2, p = 0.03) than in the primary open-angle glaucoma eyes. The pigmentary glaucoma group did not vary significantly from the primary open-angle glaucoma group in size of the optic disc. No significant differences were found for neuroretinal rim area, configuration of neuroretinal rim, depth of optic cup and diameters of the retinal arterioles and venules at the disc border between the secondary glaucoma groups and the POAG group respectively. Size of zone beta of the parapapillary atrophy was slightly, but not significantly smaller in the secondary glaucoma groups than in POAG. In the secondary glaucoma groups, the maximal intraocular pressure measurements were significantly (p < 0.001) higher than in the group with POAG. All glaucoma groups had a significantly smaller neuroretinal rim, significantly smaller retinal arterioles, and significantly larger parapapillary atrophy compared to the normal group.

CONCLUSIONS

Except of a slightly smaller optic disc in eyes with pseudoexfoliative glaucoma, eyes with secondary glaucoma due to pseudoexfoliation or due to pigmentary dispersion do not vary significantly in their optic disc morphology compared to POAG and do not show pathognomonic features of the optic disc despite marked changes in the anterior segment of the eye.

Authors+Show Affiliations

Augenklinik mit Poliklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg. Wido.Budde@augen.med.uni-erlangen.deNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

ger

PubMed ID

10572883

Citation

Budde, W M., and J B. Jonas. "[Morphology of the Optic Papilla in Glaucoma. II. Secondary Chronic Open Angle Glaucoma]." Klinische Monatsblatter Fur Augenheilkunde, vol. 215, no. 4, 1999, pp. 221-7.
Budde WM, Jonas JB. [Morphology of the optic papilla in glaucoma. II. Secondary chronic open angle glaucoma]. Klin Monbl Augenheilkd. 1999;215(4):221-7.
Budde, W. M., & Jonas, J. B. (1999). [Morphology of the optic papilla in glaucoma. II. Secondary chronic open angle glaucoma]. Klinische Monatsblatter Fur Augenheilkunde, 215(4), 221-7.
Budde WM, Jonas JB. [Morphology of the Optic Papilla in Glaucoma. II. Secondary Chronic Open Angle Glaucoma]. Klin Monbl Augenheilkd. 1999;215(4):221-7. PubMed PMID: 10572883.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Morphology of the optic papilla in glaucoma. II. Secondary chronic open angle glaucoma]. AU - Budde,W M, AU - Jonas,J B, PY - 1999/11/26/pubmed PY - 1999/11/26/medline PY - 1999/11/26/entrez SP - 221 EP - 7 JF - Klinische Monatsblatter fur Augenheilkunde JO - Klin Monbl Augenheilkd VL - 215 IS - 4 N2 - UNLABELLED: Previous studies have shown that the chronic open-angle glaucomas form a heterogeneous spectrum of diseases which have in common an open anterior chamber angle and glaucomatous optic nerve damage. Purpose of this study was to evaluate whether the appearance of the optic disc shows specific features among various types of secondary chronic open-angle glaucoma. METHODS: Clinical data and color-stereo optic disc photographs of 126 patients with pseudoexfoliative glaucoma and 47 patients with pigmentary glaucoma were compared with those of 501 patients with primary open-angle glaucoma (POAG) and of 481 normal subjects. The glaucoma groups did not differ in neuroretinal rim nor in perimetric mean defect. RESULTS: Mean optic disc area was significantly smaller in the pseudoexfoliative glaucoma eyes (2.54 +/- 0.51 mm2 vs. 2.71 +/- 0.63 mm2, p = 0.03) than in the primary open-angle glaucoma eyes. The pigmentary glaucoma group did not vary significantly from the primary open-angle glaucoma group in size of the optic disc. No significant differences were found for neuroretinal rim area, configuration of neuroretinal rim, depth of optic cup and diameters of the retinal arterioles and venules at the disc border between the secondary glaucoma groups and the POAG group respectively. Size of zone beta of the parapapillary atrophy was slightly, but not significantly smaller in the secondary glaucoma groups than in POAG. In the secondary glaucoma groups, the maximal intraocular pressure measurements were significantly (p < 0.001) higher than in the group with POAG. All glaucoma groups had a significantly smaller neuroretinal rim, significantly smaller retinal arterioles, and significantly larger parapapillary atrophy compared to the normal group. CONCLUSIONS: Except of a slightly smaller optic disc in eyes with pseudoexfoliative glaucoma, eyes with secondary glaucoma due to pseudoexfoliation or due to pigmentary dispersion do not vary significantly in their optic disc morphology compared to POAG and do not show pathognomonic features of the optic disc despite marked changes in the anterior segment of the eye. SN - 0023-2165 UR - https://www.unboundmedicine.com/medline/citation/10572883/[Morphology_of_the_optic_papilla_in_glaucoma__II__Secondary_chronic_open_angle_glaucoma]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1034703 DB - PRIME DP - Unbound Medicine ER -