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Obesity correlates with gastroesophageal reflux.
Dig Dis Sci 1999; 44(11):2290-4DD

Abstract

Thirty morbidly obese patients presenting for bariatric surgery were evaluated for symptomatic and objective evidence of gastroesophageal reflux. Sixteen patients had heartburn while 14 were asymptomatic. All underwent esophageal function testing; manometry was performed in all patients, pH monitoring in 28. Patients with esophageal pH < 4 for more than 5% of observed time weighed more than those with normal acid exposure, 165.2 vs 129.8 kg (P < 0.01), and had significantly higher body mass indices, 56.5 vs 48.3 kg/m2 (P < 0.05). Similarly, morbidly obese patients with abnormal reflux scores weighed significantly more and had greater body mass indices than patients with normal scores (P < 0.05). Lower esophageal sphincter pressure was higher in patients with normal esophageal acid exposure than in those with abnormal findings, 15.5 vs 12.5 mm Hg (P < 0.05). This study demonstrates a correlation between both weight and body mass index with gastroesophageal reflux.

Authors+Show Affiliations

Department of Surgery, University of Nevada School of Medicine, Las Vegas, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10573376

Citation

Fisher, B L., et al. "Obesity Correlates With Gastroesophageal Reflux." Digestive Diseases and Sciences, vol. 44, no. 11, 1999, pp. 2290-4.
Fisher BL, Pennathur A, Mutnick JL, et al. Obesity correlates with gastroesophageal reflux. Dig Dis Sci. 1999;44(11):2290-4.
Fisher, B. L., Pennathur, A., Mutnick, J. L., & Little, A. G. (1999). Obesity correlates with gastroesophageal reflux. Digestive Diseases and Sciences, 44(11), pp. 2290-4.
Fisher BL, et al. Obesity Correlates With Gastroesophageal Reflux. Dig Dis Sci. 1999;44(11):2290-4. PubMed PMID: 10573376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obesity correlates with gastroesophageal reflux. AU - Fisher,B L, AU - Pennathur,A, AU - Mutnick,J L, AU - Little,A G, PY - 1999/11/26/pubmed PY - 1999/11/26/medline PY - 1999/11/26/entrez SP - 2290 EP - 4 JF - Digestive diseases and sciences JO - Dig. Dis. Sci. VL - 44 IS - 11 N2 - Thirty morbidly obese patients presenting for bariatric surgery were evaluated for symptomatic and objective evidence of gastroesophageal reflux. Sixteen patients had heartburn while 14 were asymptomatic. All underwent esophageal function testing; manometry was performed in all patients, pH monitoring in 28. Patients with esophageal pH < 4 for more than 5% of observed time weighed more than those with normal acid exposure, 165.2 vs 129.8 kg (P < 0.01), and had significantly higher body mass indices, 56.5 vs 48.3 kg/m2 (P < 0.05). Similarly, morbidly obese patients with abnormal reflux scores weighed significantly more and had greater body mass indices than patients with normal scores (P < 0.05). Lower esophageal sphincter pressure was higher in patients with normal esophageal acid exposure than in those with abnormal findings, 15.5 vs 12.5 mm Hg (P < 0.05). This study demonstrates a correlation between both weight and body mass index with gastroesophageal reflux. SN - 0163-2116 UR - https://www.unboundmedicine.com/medline/citation/10573376/Obesity_correlates_with_gastroesophageal_reflux_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=10573376.ui DB - PRIME DP - Unbound Medicine ER -