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Long-term effects of distal splenorenal shunt with splenopancreatic and gastric disconnection on hypersplenism due to liver cirrhosis.
Hepatogastroenterology. 1999 Sep-Oct; 46(29):2995-8.H

Abstract

BACKGROUND/AIMS

Though the distal splenorenal shunt has been applied for gastroesophageal varices caused by liver cirrhosis, many patients develop secondary hypersplenism due to the portal hypertension following liver cirrhosis. We examined whether this operation could be effective for alleviating secondary hypersplenism for a long post-operative period. The subjects were 42 cases with gastroesophageal varices following liver cirrhosis in which we had performed distal splenorenal shunts with splenopancreatic and gastric disconnection at our institution in the period from 1983 1994 and the post-operative survival periods had been over 3 years.

METHODOLOGY

White blood cell counts, platelet counts and spleen volume were measured prior to operation, 1 month after operation and during the post-operative period of 3-5 years. Quality of life and clinical symptoms were evaluated during the post-operative period of 3-5 years.

RESULTS

White blood cell counts, platelet counts and spleen volume were improved respectively at 1 month and during the 3-5-year period after surgery, compared to those prior to operation. None of the clinical symptoms of hypersplenism were observed and the long-term performance status was satisfactory.

CONCLUSIONS

We can conclude that the distal splenorenal shunt with splenopancreatic and gastric disconnection alleviated hypersplenism for post-operatively long periods.

Authors+Show Affiliations

Miura H
Second Department of Surgery, School of Medicine, Hokkaido University, Sapporo, Japan.
Kondo S
No affiliation info available
Shimada T
No affiliation info available
Sugiura H
No affiliation info available
Morikawa T
No affiliation info available
Okushiba S
No affiliation info available
Katoh H
No affiliation info available

MeSH

AdultAgedEsophageal and Gastric VaricesFemaleFollow-Up StudiesHumansHypersplenismHypertension, PortalLiver CirrhosisMaleMiddle AgedPostoperative ComplicationsQuality of LifeReoperationSplenorenal Shunt, Surgical

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10576390

Citation

Miura, H, et al. "Long-term Effects of Distal Splenorenal Shunt With Splenopancreatic and Gastric Disconnection On Hypersplenism Due to Liver Cirrhosis." Hepato-gastroenterology, vol. 46, no. 29, 1999, pp. 2995-8.
Miura H, Kondo S, Shimada T, et al. Long-term effects of distal splenorenal shunt with splenopancreatic and gastric disconnection on hypersplenism due to liver cirrhosis. Hepatogastroenterology. 1999;46(29):2995-8.
Miura, H., Kondo, S., Shimada, T., Sugiura, H., Morikawa, T., Okushiba, S., & Katoh, H. (1999). Long-term effects of distal splenorenal shunt with splenopancreatic and gastric disconnection on hypersplenism due to liver cirrhosis. Hepato-gastroenterology, 46(29), 2995-8.
Miura H, et al. Long-term Effects of Distal Splenorenal Shunt With Splenopancreatic and Gastric Disconnection On Hypersplenism Due to Liver Cirrhosis. Hepatogastroenterology. 1999 Sep-Oct;46(29):2995-8. PubMed PMID: 10576390.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term effects of distal splenorenal shunt with splenopancreatic and gastric disconnection on hypersplenism due to liver cirrhosis. AU - Miura,H, AU - Kondo,S, AU - Shimada,T, AU - Sugiura,H, AU - Morikawa,T, AU - Okushiba,S, AU - Katoh,H, PY - 1999/11/27/pubmed PY - 1999/11/27/medline PY - 1999/11/27/entrez SP - 2995 EP - 8 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 46 IS - 29 N2 - BACKGROUND/AIMS: Though the distal splenorenal shunt has been applied for gastroesophageal varices caused by liver cirrhosis, many patients develop secondary hypersplenism due to the portal hypertension following liver cirrhosis. We examined whether this operation could be effective for alleviating secondary hypersplenism for a long post-operative period. The subjects were 42 cases with gastroesophageal varices following liver cirrhosis in which we had performed distal splenorenal shunts with splenopancreatic and gastric disconnection at our institution in the period from 1983 1994 and the post-operative survival periods had been over 3 years. METHODOLOGY: White blood cell counts, platelet counts and spleen volume were measured prior to operation, 1 month after operation and during the post-operative period of 3-5 years. Quality of life and clinical symptoms were evaluated during the post-operative period of 3-5 years. RESULTS: White blood cell counts, platelet counts and spleen volume were improved respectively at 1 month and during the 3-5-year period after surgery, compared to those prior to operation. None of the clinical symptoms of hypersplenism were observed and the long-term performance status was satisfactory. CONCLUSIONS: We can conclude that the distal splenorenal shunt with splenopancreatic and gastric disconnection alleviated hypersplenism for post-operatively long periods. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/10576390/Long_term_effects_of_distal_splenorenal_shunt_with_splenopancreatic_and_gastric_disconnection_on_hypersplenism_due_to_liver_cirrhosis_ L2 - https://medlineplus.gov/cirrhosis.html DB - PRIME DP - Unbound Medicine ER -