Novel highly oxygenated bisabolane sesquiterpenes from Cremanthodium discoideum.J Nat Prod. 1999 Nov; 62(11):1479-83.JN
Five new highly oxygenated bisabolane sesquiterpenes (1-5) were isolated from Cremanthodium discoideum. Their structures were elucidated on the basis of spectroscopic analysis and chemical transformations. The structure and relative stereochemistry of 1 were determined by single-crystal X-ray crystallography on the acetate derivative, 1a. Compound 1 showed antibacterial activity against Bacillus acidilatici and Bacillus subtilis.