Tags

Type your tag names separated by a space and hit enter

Control of a prolonged outbreak of extended-spectrum beta-lactamase-producing enterobacteriaceae in a university hospital.
Clin Infect Dis. 1999 Dec; 29(6):1411-8.CI

Abstract

Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBLPE) were isolated from clinical specimens from 130 to 140 patients/year in 1989-1991 in our hospital. In February 1992, a control program was initiated: screening tests in 3 intensive care units (ICUs) and contact-isolation precautions in all units. The septic surgical unit served as an isolation ward for surgical patients from whom ESBLPE was isolated. In 1992, the incidence of ESBLPE acquisition failed to decrease, and most acquisitions occurred in 3 ICUs. Critical evaluation of implementation of isolation procedures in these ICUs prompted corrective measures for barrier precautions. The incidence of acquired cases subsequently decreased, and a second evaluation determined that these measures had been correctly applied. The incidence of acquired cases in the septic surgical unit was lower than those in the other units. Decreases were also found in the incidence of acquisition of other hand-transmitted multidrug-resistant organisms. Barrier precautions, screening tests for ICU patients, and grouping of cohorts after ICU discharge are effective in controlling the spread of multidrug-resistant microorganisms by cross-contamination. The outbreak was effectively controlled without restricting antimicrobial use.

Authors+Show Affiliations

Unité d'Hygiène et de Lutte contre l'Infection Nosocomiale, Group Hospitalier Bichat-Claude Bernard, Paris, France. jean-christophe. lucet@bch.ap-hop-paris.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10585788

Citation

Lucet, J C., et al. "Control of a Prolonged Outbreak of Extended-spectrum Beta-lactamase-producing Enterobacteriaceae in a University Hospital." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 29, no. 6, 1999, pp. 1411-8.
Lucet JC, Decré D, Fichelle A, et al. Control of a prolonged outbreak of extended-spectrum beta-lactamase-producing enterobacteriaceae in a university hospital. Clin Infect Dis. 1999;29(6):1411-8.
Lucet, J. C., Decré, D., Fichelle, A., Joly-Guillou, M. L., Pernet, M., Deblangy, C., Kosmann, M. J., & Régnier, B. (1999). Control of a prolonged outbreak of extended-spectrum beta-lactamase-producing enterobacteriaceae in a university hospital. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 29(6), 1411-8.
Lucet JC, et al. Control of a Prolonged Outbreak of Extended-spectrum Beta-lactamase-producing Enterobacteriaceae in a University Hospital. Clin Infect Dis. 1999;29(6):1411-8. PubMed PMID: 10585788.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Control of a prolonged outbreak of extended-spectrum beta-lactamase-producing enterobacteriaceae in a university hospital. AU - Lucet,J C, AU - Decré,D, AU - Fichelle,A, AU - Joly-Guillou,M L, AU - Pernet,M, AU - Deblangy,C, AU - Kosmann,M J, AU - Régnier,B, PY - 1999/12/10/pubmed PY - 2000/3/21/medline PY - 1999/12/10/entrez SP - 1411 EP - 8 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin. Infect. Dis. VL - 29 IS - 6 N2 - Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBLPE) were isolated from clinical specimens from 130 to 140 patients/year in 1989-1991 in our hospital. In February 1992, a control program was initiated: screening tests in 3 intensive care units (ICUs) and contact-isolation precautions in all units. The septic surgical unit served as an isolation ward for surgical patients from whom ESBLPE was isolated. In 1992, the incidence of ESBLPE acquisition failed to decrease, and most acquisitions occurred in 3 ICUs. Critical evaluation of implementation of isolation procedures in these ICUs prompted corrective measures for barrier precautions. The incidence of acquired cases subsequently decreased, and a second evaluation determined that these measures had been correctly applied. The incidence of acquired cases in the septic surgical unit was lower than those in the other units. Decreases were also found in the incidence of acquisition of other hand-transmitted multidrug-resistant organisms. Barrier precautions, screening tests for ICU patients, and grouping of cohorts after ICU discharge are effective in controlling the spread of multidrug-resistant microorganisms by cross-contamination. The outbreak was effectively controlled without restricting antimicrobial use. SN - 1058-4838 UR - https://www.unboundmedicine.com/medline/citation/10585788/Control_of_a_prolonged_outbreak_of_extended_spectrum_beta_lactamase_producing_enterobacteriaceae_in_a_university_hospital_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/313511 DB - PRIME DP - Unbound Medicine ER -