Tags

Type your tag names separated by a space and hit enter

Capillary electrophoresis in clinical and forensic analysis: recent advances and breakthrough to routine applications.
Electrophoresis. 1999 Oct; 20(15-16):3203-36.E

Abstract

This paper is a comprehensive review article on capillary electrophoresis (CE) in clinical and forensic analysis. It is based upon the literature of 1997 and 1998, presents CE examples in major fields of application, and provides an overview of the key achievements encountered, including those associated with the analysis of drugs, serum proteins, hemoglobin variants, and nucleic acids. For CE in clinical and forensic analysis, the past two years witnessed a breakthrough to routine applications. As most coauthors of this review are associated with diagnostic or forensic laboratories now using CE on a routine basis, this review also contains data from routine applications in drug, protein, and DNA analysis. With the first-hand experience of providing analytical service under stringent quality control conditions, aspects of quality assurance, assay specifications for clinical and forensic CE and the pros and cons of this maturing, cost-and pollution-controlled age technology are also discussed.

Authors+Show Affiliations

Thormann W
Department of Clinical Pharmacology, University of Bern, Switzerland. wolfgang.thormann@ikp.unibe.ch
Wey AB
No affiliation info available
Lurie IS
No affiliation info available
Gerber H
No affiliation info available
Byland C
No affiliation info available
Malik N
No affiliation info available
Hochmeister M
No affiliation info available
Gehrig C
No affiliation info available

MeSH

Electrophoresis, CapillaryForensic MedicineHumansNucleic AcidsPharmaceutical PreparationsProteinsResearchResearch Design

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

10596826

Citation

Thormann, W, et al. "Capillary Electrophoresis in Clinical and Forensic Analysis: Recent Advances and Breakthrough to Routine Applications." Electrophoresis, vol. 20, no. 15-16, 1999, pp. 3203-36.
Thormann W, Wey AB, Lurie IS, et al. Capillary electrophoresis in clinical and forensic analysis: recent advances and breakthrough to routine applications. Electrophoresis. 1999;20(15-16):3203-36.
Thormann, W., Wey, A. B., Lurie, I. S., Gerber, H., Byland, C., Malik, N., Hochmeister, M., & Gehrig, C. (1999). Capillary electrophoresis in clinical and forensic analysis: recent advances and breakthrough to routine applications. Electrophoresis, 20(15-16), 3203-36.
Thormann W, et al. Capillary Electrophoresis in Clinical and Forensic Analysis: Recent Advances and Breakthrough to Routine Applications. Electrophoresis. 1999;20(15-16):3203-36. PubMed PMID: 10596826.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Capillary electrophoresis in clinical and forensic analysis: recent advances and breakthrough to routine applications. AU - Thormann,W, AU - Wey,A B, AU - Lurie,I S, AU - Gerber,H, AU - Byland,C, AU - Malik,N, AU - Hochmeister,M, AU - Gehrig,C, PY - 1999/12/22/pubmed PY - 2000/8/12/medline PY - 1999/12/22/entrez SP - 3203 EP - 36 JF - Electrophoresis JO - Electrophoresis VL - 20 IS - 15-16 N2 - This paper is a comprehensive review article on capillary electrophoresis (CE) in clinical and forensic analysis. It is based upon the literature of 1997 and 1998, presents CE examples in major fields of application, and provides an overview of the key achievements encountered, including those associated with the analysis of drugs, serum proteins, hemoglobin variants, and nucleic acids. For CE in clinical and forensic analysis, the past two years witnessed a breakthrough to routine applications. As most coauthors of this review are associated with diagnostic or forensic laboratories now using CE on a routine basis, this review also contains data from routine applications in drug, protein, and DNA analysis. With the first-hand experience of providing analytical service under stringent quality control conditions, aspects of quality assurance, assay specifications for clinical and forensic CE and the pros and cons of this maturing, cost-and pollution-controlled age technology are also discussed. SN - 0173-0835 UR - https://www.unboundmedicine.com/medline/citation/10596826/Capillary_electrophoresis_in_clinical_and_forensic_analysis:_recent_advances_and_breakthrough_to_routine_applications_ L2 - https://doi.org/10.1002/(SICI)1522-2683(19991001)20:15/16<3203::AID-ELPS3203>3.0.CO;2-E DB - PRIME DP - Unbound Medicine ER -