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Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro.
Pharmacol Res. 2000 Jan; 41(1):85-8.PR

Abstract

Two kaempferol coumaroyl glycosides (i.e. platanoside and tiliroside) isolated from the methanolic extract of Platanus orientalis L. buds, were examined for their in vitro cytotoxic activity against a panel of human leukaemic cell lines. Platanoside (1) exhibited cytotoxic activity against most of the cell lines tested, while tiliroside (2) was active against two of the nine tested cell lines. Compound 1, was examined for its effect on the uptake of [(3)H]thymidine as a marker of DNA synthesis. Kaempferol was used as a control.

Authors+Show Affiliations

Department of Immunology, Hellenic Anticancer Institute, Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10600274

Citation

Dimas, K, et al. "Cytotoxic Activity of Kaempferol Glycosides Against Human Leukaemic Cell Lines in Vitro." Pharmacological Research, vol. 41, no. 1, 2000, pp. 85-8.
Dimas K, Demetzos C, Mitaku S, et al. Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro. Pharmacol Res. 2000;41(1):85-8.
Dimas, K., Demetzos, C., Mitaku, S., Marselos, M., Tzavaras, T., & Kokkinopoulos, D. (2000). Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro. Pharmacological Research, 41(1), 85-8.
Dimas K, et al. Cytotoxic Activity of Kaempferol Glycosides Against Human Leukaemic Cell Lines in Vitro. Pharmacol Res. 2000;41(1):85-8. PubMed PMID: 10600274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro. AU - Dimas,K, AU - Demetzos,C, AU - Mitaku,S, AU - Marselos,M, AU - Tzavaras,T, AU - Kokkinopoulos,D, PY - 1999/12/22/pubmed PY - 2000/3/11/medline PY - 1999/12/22/entrez SP - 85 EP - 8 JF - Pharmacological research JO - Pharmacol Res VL - 41 IS - 1 N2 - Two kaempferol coumaroyl glycosides (i.e. platanoside and tiliroside) isolated from the methanolic extract of Platanus orientalis L. buds, were examined for their in vitro cytotoxic activity against a panel of human leukaemic cell lines. Platanoside (1) exhibited cytotoxic activity against most of the cell lines tested, while tiliroside (2) was active against two of the nine tested cell lines. Compound 1, was examined for its effect on the uptake of [(3)H]thymidine as a marker of DNA synthesis. Kaempferol was used as a control. SN - 1043-6618 UR - https://www.unboundmedicine.com/medline/citation/10600274/Cytotoxic_activity_of_kaempferol_glycosides_against_human_leukaemic_cell_lines_in_vitro_ L2 - https://linkinghub.elsevier.com/retrieve/pii/phrs.1999.0562 DB - PRIME DP - Unbound Medicine ER -