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[Liver and pregnancy].
Pathol Biol (Paris). 1999 Nov; 47(9):958-65.PB

Abstract

Transaminase level elevation during pregnancy should be viewed as abnormal and evaluated. A high index of suspicion for acute fatty liver of pregnancy should be maintained during the third trimester, since early delivery has radically transformed the maternal and fetal prognosis of this condition. Pruritus is the main symptom of intrahepatic cholestasis, which carries a risk for the fetus. Urinary tract infection can cause cholestasis or worsen intrahepatic cholestasis of pregnancy. In patients with preeclampsia, rapid delivery should be considered if there is evidence of HELLP syndrome. Patients with mild chronic viral hepatitis can usually carry a pregnancy to term without undue difficulty. Neonates born to HBsAg-positive mothers should receive HBV-Ig and vaccine at birth to prevent perinatal transmission of the HBV. In patients with chronic hepatitis C, serum transaminase levels often return to normal during pregnancy, although the virus remains detectable in the blood. Mother-to-infant transmission of the HCV is possible but fairly uncommon if the mother is HIV-negative.

Authors+Show Affiliations

Service d'Hépatogastroentérologie, Hôpital Trousseau, Tours, France.

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

10609276

Citation

Bacq, Y. "[Liver and Pregnancy]." Pathologie-biologie, vol. 47, no. 9, 1999, pp. 958-65.
Bacq Y. [Liver and pregnancy]. Pathol Biol (Paris). 1999;47(9):958-65.
Bacq, Y. (1999). [Liver and pregnancy]. Pathologie-biologie, 47(9), 958-65.
Bacq Y. [Liver and Pregnancy]. Pathol Biol (Paris). 1999;47(9):958-65. PubMed PMID: 10609276.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Liver and pregnancy]. A1 - Bacq,Y, PY - 1999/12/28/pubmed PY - 1999/12/28/medline PY - 1999/12/28/entrez SP - 958 EP - 65 JF - Pathologie-biologie JO - Pathol Biol (Paris) VL - 47 IS - 9 N2 - Transaminase level elevation during pregnancy should be viewed as abnormal and evaluated. A high index of suspicion for acute fatty liver of pregnancy should be maintained during the third trimester, since early delivery has radically transformed the maternal and fetal prognosis of this condition. Pruritus is the main symptom of intrahepatic cholestasis, which carries a risk for the fetus. Urinary tract infection can cause cholestasis or worsen intrahepatic cholestasis of pregnancy. In patients with preeclampsia, rapid delivery should be considered if there is evidence of HELLP syndrome. Patients with mild chronic viral hepatitis can usually carry a pregnancy to term without undue difficulty. Neonates born to HBsAg-positive mothers should receive HBV-Ig and vaccine at birth to prevent perinatal transmission of the HBV. In patients with chronic hepatitis C, serum transaminase levels often return to normal during pregnancy, although the virus remains detectable in the blood. Mother-to-infant transmission of the HCV is possible but fairly uncommon if the mother is HIV-negative. SN - 0369-8114 UR - https://www.unboundmedicine.com/medline/citation/10609276/[Liver_and_pregnancy]_ L2 - http://www.diseaseinfosearch.org/result/5922 DB - PRIME DP - Unbound Medicine ER -