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A prospective cohort study on consumption of alcoholic beverages in relation to prostate cancer incidence (The Netherlands).

Abstract

OBJECTIVES

To examine alcohol consumption in relation to prostate cancer incidence in the Netherlands Cohort Study.

METHODS

At baseline in 1986, 58,279 men aged 55-69 years completed a self-administered questionnaire on diet, consumption of alcoholic beverages and other risk factors for cancer. For data processing and analyses the case-cohort approach was used. After 6.3 years of follow-up, 680 incident primary prostate cancer cases were available for analysis.

RESULTS

In multivariate analyses adjusted for age, socioeconomic status and family history of prostate cancer, no association between total alcohol consumption, alcohol intake from beer and liquor and prostate cancer risk was found. Increased associations were found for alcohol from white wine and fortified wines compared to nondrinkers, but not for red wine. The RRs (95% CI) in the intake category of > or = 15 g/day were 3.3 (1.2-9.2) and 2.3 (1.2-4.7), respectively, after additional adjustment for total alcohol intake. There was, however, no significant trend in risk. Alcohol intake was more strongly related with localized than with advanced prostate tumors.

CONCLUSION

Our results do not support an important role for alcohol in prostate cancer etiology. Nevertheless, for specific types of alcoholic beverages, particularly wines, a positive association was suggested which needs examination in further studies.

Links

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  • Authors+Show Affiliations

    ,

    Department of Epidemiology, Maastricht University, The Netherlands. Agnes.Schuurman@hag.unimaas.nl

    ,

    Source

    Cancer causes & control : CCC 10:6 1999 Dec pg 597-605

    MeSH

    Age Distribution
    Aged
    Alcohol Drinking
    Cohort Studies
    Confidence Intervals
    Diet
    Humans
    Incidence
    Male
    Middle Aged
    Multivariate Analysis
    Netherlands
    Prospective Studies
    Prostatic Neoplasms
    Socioeconomic Factors
    Surveys and Questionnaires

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    10616828

    Citation

    Schuurman, A G., et al. "A Prospective Cohort Study On Consumption of Alcoholic Beverages in Relation to Prostate Cancer Incidence (The Netherlands)." Cancer Causes & Control : CCC, vol. 10, no. 6, 1999, pp. 597-605.
    Schuurman AG, Goldbohm RA, van den Brandt PA. A prospective cohort study on consumption of alcoholic beverages in relation to prostate cancer incidence (The Netherlands). Cancer Causes Control. 1999;10(6):597-605.
    Schuurman, A. G., Goldbohm, R. A., & van den Brandt, P. A. (1999). A prospective cohort study on consumption of alcoholic beverages in relation to prostate cancer incidence (The Netherlands). Cancer Causes & Control : CCC, 10(6), pp. 597-605.
    Schuurman AG, Goldbohm RA, van den Brandt PA. A Prospective Cohort Study On Consumption of Alcoholic Beverages in Relation to Prostate Cancer Incidence (The Netherlands). Cancer Causes Control. 1999;10(6):597-605. PubMed PMID: 10616828.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - A prospective cohort study on consumption of alcoholic beverages in relation to prostate cancer incidence (The Netherlands). AU - Schuurman,A G, AU - Goldbohm,R A, AU - van den Brandt,P A, PY - 2000/1/5/pubmed PY - 2000/1/5/medline PY - 2000/1/5/entrez SP - 597 EP - 605 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 10 IS - 6 N2 - OBJECTIVES: To examine alcohol consumption in relation to prostate cancer incidence in the Netherlands Cohort Study. METHODS: At baseline in 1986, 58,279 men aged 55-69 years completed a self-administered questionnaire on diet, consumption of alcoholic beverages and other risk factors for cancer. For data processing and analyses the case-cohort approach was used. After 6.3 years of follow-up, 680 incident primary prostate cancer cases were available for analysis. RESULTS: In multivariate analyses adjusted for age, socioeconomic status and family history of prostate cancer, no association between total alcohol consumption, alcohol intake from beer and liquor and prostate cancer risk was found. Increased associations were found for alcohol from white wine and fortified wines compared to nondrinkers, but not for red wine. The RRs (95% CI) in the intake category of > or = 15 g/day were 3.3 (1.2-9.2) and 2.3 (1.2-4.7), respectively, after additional adjustment for total alcohol intake. There was, however, no significant trend in risk. Alcohol intake was more strongly related with localized than with advanced prostate tumors. CONCLUSION: Our results do not support an important role for alcohol in prostate cancer etiology. Nevertheless, for specific types of alcoholic beverages, particularly wines, a positive association was suggested which needs examination in further studies. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/10616828/A_prospective_cohort_study_on_consumption_of_alcoholic_beverages_in_relation_to_prostate_cancer_incidence__The_Netherlands__ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=10616828.ui DB - PRIME DP - Unbound Medicine ER -