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Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea.
Planta Med. 1999 Dec; 65(8):752-4.PM

Abstract

The chemical composition of the essential oils of Salvia desoleana Atzei & Picci and Salvia sclarea L. from Sardinia (Italy) was analysed by GC and GC/MS. S. desoleana oil had a high content of monoterpenic esters (linalyl acetate and alpha-terpinyl acetate) and a lower amount of the corresponding alcohols while S. sclarea oil was characterised by a higher content of alcohols and lower quantity of esters. We studied the antimicrobial activity of these oils concerning their use in pharmaceutical preparations for local application. Only weak microbiostatic inhibitory activity was seen against S. aureus, E. coli, S. epidermidis and C. albicans, but since inhibition increased progressively with contact time, better results could be obtained by using these oils in bioadhesive formulations that would also have anti-inflammatory and peripheral analgesic action at a local level, as demonstrated in experimental animals following systemic application.

Authors

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Pub Type(s)

Letter

Language

eng

PubMed ID

10630121

Citation

Peana, A T., et al. "Chemical Composition and Antimicrobial Action of the Essential Oils of Salvia Desoleana and S. Sclarea." Planta Medica, vol. 65, no. 8, 1999, pp. 752-4.
Peana AT, Moretti MD, Juliano C. Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea. Planta Med. 1999;65(8):752-4.
Peana, A. T., Moretti, M. D., & Juliano, C. (1999). Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea. Planta Medica, 65(8), 752-4.
Peana AT, Moretti MD, Juliano C. Chemical Composition and Antimicrobial Action of the Essential Oils of Salvia Desoleana and S. Sclarea. Planta Med. 1999;65(8):752-4. PubMed PMID: 10630121.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea. AU - Peana,A T, AU - Moretti,M D, AU - Juliano,C, PY - 2000/1/12/pubmed PY - 2000/2/19/medline PY - 2000/1/12/entrez SP - 752 EP - 4 JF - Planta medica JO - Planta Med VL - 65 IS - 8 N2 - The chemical composition of the essential oils of Salvia desoleana Atzei & Picci and Salvia sclarea L. from Sardinia (Italy) was analysed by GC and GC/MS. S. desoleana oil had a high content of monoterpenic esters (linalyl acetate and alpha-terpinyl acetate) and a lower amount of the corresponding alcohols while S. sclarea oil was characterised by a higher content of alcohols and lower quantity of esters. We studied the antimicrobial activity of these oils concerning their use in pharmaceutical preparations for local application. Only weak microbiostatic inhibitory activity was seen against S. aureus, E. coli, S. epidermidis and C. albicans, but since inhibition increased progressively with contact time, better results could be obtained by using these oils in bioadhesive formulations that would also have anti-inflammatory and peripheral analgesic action at a local level, as demonstrated in experimental animals following systemic application. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/10630121/Chemical_composition_and_antimicrobial_action_of_the_essential_oils_of_Salvia_desoleana_and_S__sclarea_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-960857 DB - PRIME DP - Unbound Medicine ER -