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[Periconceptual folic acid intake by Sicilian couples at a risk of recurrence of NTD].
Minerva Ginecol 1999; 51(10):399-401MG

Abstract

BACKGROUND AND AIM

The authors aimed to evaluate the frequency with which pregnant Sicilian women with a high risk of recurring neural tube defects (NTD) attending the Ultrasonography and Prenatal Diagnosis Clinic in the Department of Diagnosis and Treatment at Ospedale S. Bambino in Catania were aware of the preventive effect of folic acid supplements during the periconceptional period and whether they therefore took folic acid supplements before the next pregnancy.

METHODS

All pregnant women undergoing ultrasonography between January 1997 and December 1998 were interviewed. It was noted whether any earlier offspring had suffered from NTD or whether relatives (sisters, brothers, parents) had also suffered from the same experience. They were also asked whether they knew about the preventive effect of periconceptional folic acid supplements on the development of NTD, whether their pregnancy was planned and whether they had taken periconceptional folic acid supplements and, if so, at what dose.

RESULTS

Eighteen couples were identified as being at risk for recurring NTD, in 3 cases owing to an earlier pregnancy resulting in NTD (2 cases of spina bifida and 1 case of anencephaly) with a negative family history for NTD; a further 15 couples showed a positive family history for NTD. None of the women were aware of the preventive effect of acid folic supplements during the periconceptional period on the development of NTD. Out of 11 programmed pregnancies, none of the pregnant women took folic acid during the periconceptional phase.

CONCLUSIONS

Pregnant Sicilian women at risk for recurring NTD interviewed by the authors were not aware of the possible prevention of NTD using folic acid supplements during the periconceptional phase.

Authors+Show Affiliations

I Divisione di Diagnosi e Cura Ambulatorio di Ecografia e Diagnosi Prenatale, Ospedale di Maternità S. Bambino, Catania.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

10638166

Citation

Pepe, F, et al. "[Periconceptual Folic Acid Intake By Sicilian Couples at a Risk of Recurrence of NTD]." Minerva Ginecologica, vol. 51, no. 10, 1999, pp. 399-401.
Pepe F, Pepe P, Grillo S, et al. [Periconceptual folic acid intake by Sicilian couples at a risk of recurrence of NTD]. Minerva Ginecol. 1999;51(10):399-401.
Pepe, F., Pepe, P., Grillo, S., & Insolia, G. (1999). [Periconceptual folic acid intake by Sicilian couples at a risk of recurrence of NTD]. Minerva Ginecologica, 51(10), pp. 399-401.
Pepe F, et al. [Periconceptual Folic Acid Intake By Sicilian Couples at a Risk of Recurrence of NTD]. Minerva Ginecol. 1999;51(10):399-401. PubMed PMID: 10638166.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Periconceptual folic acid intake by Sicilian couples at a risk of recurrence of NTD]. AU - Pepe,F, AU - Pepe,P, AU - Grillo,S, AU - Insolia,G, PY - 2000/1/19/pubmed PY - 2000/1/19/medline PY - 2000/1/19/entrez SP - 399 EP - 401 JF - Minerva ginecologica JO - Minerva Ginecol VL - 51 IS - 10 N2 - BACKGROUND AND AIM: The authors aimed to evaluate the frequency with which pregnant Sicilian women with a high risk of recurring neural tube defects (NTD) attending the Ultrasonography and Prenatal Diagnosis Clinic in the Department of Diagnosis and Treatment at Ospedale S. Bambino in Catania were aware of the preventive effect of folic acid supplements during the periconceptional period and whether they therefore took folic acid supplements before the next pregnancy. METHODS: All pregnant women undergoing ultrasonography between January 1997 and December 1998 were interviewed. It was noted whether any earlier offspring had suffered from NTD or whether relatives (sisters, brothers, parents) had also suffered from the same experience. They were also asked whether they knew about the preventive effect of periconceptional folic acid supplements on the development of NTD, whether their pregnancy was planned and whether they had taken periconceptional folic acid supplements and, if so, at what dose. RESULTS: Eighteen couples were identified as being at risk for recurring NTD, in 3 cases owing to an earlier pregnancy resulting in NTD (2 cases of spina bifida and 1 case of anencephaly) with a negative family history for NTD; a further 15 couples showed a positive family history for NTD. None of the women were aware of the preventive effect of acid folic supplements during the periconceptional period on the development of NTD. Out of 11 programmed pregnancies, none of the pregnant women took folic acid during the periconceptional phase. CONCLUSIONS: Pregnant Sicilian women at risk for recurring NTD interviewed by the authors were not aware of the possible prevention of NTD using folic acid supplements during the periconceptional phase. SN - 0026-4784 UR - https://www.unboundmedicine.com/medline/citation/10638166/[Periconceptual_folic_acid_intake_by_Sicilian_couples_at_a_risk_of_recurrence_of_NTD]_ L2 - https://medlineplus.gov/neuraltubedefects.html DB - PRIME DP - Unbound Medicine ER -