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New drugs for the treatment of Parkinson's disease.
Pharmacotherapy. 2000 Jan; 20(1 Pt 2):26S-32S.P

Abstract

Since the introduction of levodopa to treat Parkinson's disease (PD), several new therapies have been directed at improving symptom control, which can decline after a few years of levodopa therapy. Dopaminergic agents can serve as adjuncts or as alternatives to levodopa. In addition, a new class of drugs, catechol-O-methyltransferase inhibitors, can extend the duration of levodopa action. Although surgical options such as pallidotomy offer improvement of parkinsonism beyond the realm of pharmacologic treatment, judicious administration of drugs in combination can generally solve most problems of PD.

Authors+Show Affiliations

Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

10641989

Citation

LeWitt, P A.. "New Drugs for the Treatment of Parkinson's Disease." Pharmacotherapy, vol. 20, no. 1 Pt 2, 2000, 26S-32S.
LeWitt PA. New drugs for the treatment of Parkinson's disease. Pharmacotherapy. 2000;20(1 Pt 2):26S-32S.
LeWitt, P. A. (2000). New drugs for the treatment of Parkinson's disease. Pharmacotherapy, 20(1 Pt 2), 26S-32S.
LeWitt PA. New Drugs for the Treatment of Parkinson's Disease. Pharmacotherapy. 2000;20(1 Pt 2):26S-32S. PubMed PMID: 10641989.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New drugs for the treatment of Parkinson's disease. A1 - LeWitt,P A, PY - 2000/1/21/pubmed PY - 2000/1/21/medline PY - 2000/1/21/entrez SP - 26S EP - 32S JF - Pharmacotherapy JO - Pharmacotherapy VL - 20 IS - 1 Pt 2 N2 - Since the introduction of levodopa to treat Parkinson's disease (PD), several new therapies have been directed at improving symptom control, which can decline after a few years of levodopa therapy. Dopaminergic agents can serve as adjuncts or as alternatives to levodopa. In addition, a new class of drugs, catechol-O-methyltransferase inhibitors, can extend the duration of levodopa action. Although surgical options such as pallidotomy offer improvement of parkinsonism beyond the realm of pharmacologic treatment, judicious administration of drugs in combination can generally solve most problems of PD. SN - 0277-0008 UR - https://www.unboundmedicine.com/medline/citation/10641989/New_drugs_for_the_treatment_of_Parkinson's_disease_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0277-0008&date=2000&volume=20&issue=1 Pt 2&spage=26S DB - PRIME DP - Unbound Medicine ER -