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Influence of fibroblast growth factor, insulin-like growth factor I, and transforming growth factor beta on satellite cell type I collagen expression and localization during differentiation.
Cytobios. 1999; 100(394):101-10.C

Abstract

Expression, and temporal and spatial distribution of type I collagen were investigated in chicken satellite cell cultures during differentiation. There was no difference in the relative amounts of type I collagen after treatment with basic fibroblast growth factor (FGF), insulin-like growth factor-I (IGF-I), or transforming growth factor beta 1 (TGF-beta 1). However, myotube morphology was influenced by the presence of the growth factors. The temporal and spatial distribution of type I collagen was also modified. Control cultures maintained a predominant distribution of type I collagen surrounding the cellular area until approximately 48 h after the initiation of fusion whereas cultures with FGF or IGF-I maintained a cellular localization of type I collagen throughout the fusion process. TGF-beta 1 resulted in the early formation of an extracellular network of type I collagen preceding control cultures by approximately 24 h. These results suggest that type I collagen expression but not localization is independent of satellite cell proliferation and differentiation.

Authors+Show Affiliations

Department of Animal Sciences, Ohio State University/Ohio Agricultural Research and Development Center, Wooster, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

10643646

Citation

Velleman, S G., and D C. McFarland. "Influence of Fibroblast Growth Factor, Insulin-like Growth Factor I, and Transforming Growth Factor Beta On Satellite Cell Type I Collagen Expression and Localization During Differentiation." Cytobios, vol. 100, no. 394, 1999, pp. 101-10.
Velleman SG, McFarland DC. Influence of fibroblast growth factor, insulin-like growth factor I, and transforming growth factor beta on satellite cell type I collagen expression and localization during differentiation. Cytobios. 1999;100(394):101-10.
Velleman, S. G., & McFarland, D. C. (1999). Influence of fibroblast growth factor, insulin-like growth factor I, and transforming growth factor beta on satellite cell type I collagen expression and localization during differentiation. Cytobios, 100(394), 101-10.
Velleman SG, McFarland DC. Influence of Fibroblast Growth Factor, Insulin-like Growth Factor I, and Transforming Growth Factor Beta On Satellite Cell Type I Collagen Expression and Localization During Differentiation. Cytobios. 1999;100(394):101-10. PubMed PMID: 10643646.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of fibroblast growth factor, insulin-like growth factor I, and transforming growth factor beta on satellite cell type I collagen expression and localization during differentiation. AU - Velleman,S G, AU - McFarland,D C, PY - 2000/1/22/pubmed PY - 2000/2/19/medline PY - 2000/1/22/entrez SP - 101 EP - 10 JF - Cytobios JO - Cytobios VL - 100 IS - 394 N2 - Expression, and temporal and spatial distribution of type I collagen were investigated in chicken satellite cell cultures during differentiation. There was no difference in the relative amounts of type I collagen after treatment with basic fibroblast growth factor (FGF), insulin-like growth factor-I (IGF-I), or transforming growth factor beta 1 (TGF-beta 1). However, myotube morphology was influenced by the presence of the growth factors. The temporal and spatial distribution of type I collagen was also modified. Control cultures maintained a predominant distribution of type I collagen surrounding the cellular area until approximately 48 h after the initiation of fusion whereas cultures with FGF or IGF-I maintained a cellular localization of type I collagen throughout the fusion process. TGF-beta 1 resulted in the early formation of an extracellular network of type I collagen preceding control cultures by approximately 24 h. These results suggest that type I collagen expression but not localization is independent of satellite cell proliferation and differentiation. SN - 0011-4529 UR - https://www.unboundmedicine.com/medline/citation/10643646/Influence_of_fibroblast_growth_factor_insulin_like_growth_factor_I_and_transforming_growth_factor_beta_on_satellite_cell_type_I_collagen_expression_and_localization_during_differentiation_ L2 - https://antibodies.cancer.gov/detail/CPTC-TGFB1-1 DB - PRIME DP - Unbound Medicine ER -