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Antibacterial and antifungal flavanones from Eysenhardtia texana.
Phytochemistry. 1999 Dec; 52(8):1469-71.P

Abstract

An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana led to the isolation of two novel antibacterial and antifungal flavanones together with a known flavanone. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone, 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5-dihydroxy-7-methoxy-6-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, 1D and 2D-NMR spectra.

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Authors+Show Affiliations

Wächter GA
Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson 85706, USA.
Hoffmann JJ
No affiliation info available
Furbacher T
No affiliation info available
Blake ME
No affiliation info available
Timmermann BN
No affiliation info available

MeSH

Anti-Bacterial AgentsAnti-Infective AgentsAntifungal AgentsCandida albicansFlavonoidsMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsPlant ExtractsPlantsSpectrometry, Mass, Secondary IonStaphylococcus aureus

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10647219

Citation

Wächter, G A., et al. "Antibacterial and Antifungal Flavanones From Eysenhardtia Texana." Phytochemistry, vol. 52, no. 8, 1999, pp. 1469-71.
Wächter GA, Hoffmann JJ, Furbacher T, et al. Antibacterial and antifungal flavanones from Eysenhardtia texana. Phytochemistry. 1999;52(8):1469-71.
Wächter, G. A., Hoffmann, J. J., Furbacher, T., Blake, M. E., & Timmermann, B. N. (1999). Antibacterial and antifungal flavanones from Eysenhardtia texana. Phytochemistry, 52(8), 1469-71.
Wächter GA, et al. Antibacterial and Antifungal Flavanones From Eysenhardtia Texana. Phytochemistry. 1999;52(8):1469-71. PubMed PMID: 10647219.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibacterial and antifungal flavanones from Eysenhardtia texana. AU - Wächter,G A, AU - Hoffmann,J J, AU - Furbacher,T, AU - Blake,M E, AU - Timmermann,B N, PY - 2000/1/27/pubmed PY - 2000/2/26/medline PY - 2000/1/27/entrez SP - 1469 EP - 71 JF - Phytochemistry JO - Phytochemistry VL - 52 IS - 8 N2 - An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana led to the isolation of two novel antibacterial and antifungal flavanones together with a known flavanone. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone, 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5-dihydroxy-7-methoxy-6-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, 1D and 2D-NMR spectra. SN - 0031-9422 UR - https://www.unboundmedicine.com/medline/citation/10647219/Antibacterial_and_antifungal_flavanones_from_Eysenhardtia_texana_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-9422(99)00221-6 DB - PRIME DP - Unbound Medicine ER -