Tags

Type your tag names separated by a space and hit enter

Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study.

Abstract

PURPOSE

We examined whether the prevalence of benign prostatic hyperplasia (BPH) varies by racial or ethnic origin in a large cohort of American male health professionals.

MATERIALS AND METHODS

Included in our study were 1,508 men who underwent surgery for BPH between 1986 and 1994, and 1,837 with high moderate to severe lower urinary tract symptoms assessed by the American Urological Association symptom index in 1992 or 1994. "Noncases" comprised 23,246 asymptomatic participants. Self-reported major ancestry was black in 201 men, Asian in 413, other origin in 604 and white in 25,373. White heritage was further classified as southern European in 6,408 men, Scandinavian in 2,951 and other white in 16,014. The relative risk of BPH and 95% confidence intervals (CI) adjusted for age, body mass index, alcohol consumption, smoking and physical activity were calculated by logistic regression.

RESULTS

Black men were not at increased risk for BPH (relative risk 0.85, 95% CI 0.55 to 1.31) compared with white men. Asian men were less likely to have undergone BPH surgery (relative risk 0.41, 95% CI 0.21 to 0.82), although the relative risk for symptoms was similar to that of white men. White men whose major ancestry was southern European were at modestly higher risk for BPH surgery (relative risk 1.28, 95% CI 1.12 to 1.46) and symptoms (relative risk 1.34, 95% CI 1.20 to 1.50), whereas men of Scandinavian heritage were at slightly decreased risk for symptoms than those of other white heritages.

CONCLUSIONS

Racial and ethnic variation is evident in the incidence of BPH surgery and symptom severity. Whether this observed variation reflects underlying biological phenomena rather than differences in symptom tolerance requires further exploration.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.

    , , ,

    Source

    The Journal of urology 163:2 2000 Feb pg 490-5

    MeSH

    Adult
    Aged
    Continental Population Groups
    Ethnic Groups
    Follow-Up Studies
    Health Personnel
    Humans
    Male
    Middle Aged
    Prospective Studies
    Prostatic Hyperplasia
    Risk

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    10647663

    Citation

    Platz, E A., et al. "Race, Ethnicity and Benign Prostatic Hyperplasia in the Health Professionals Follow-up Study." The Journal of Urology, vol. 163, no. 2, 2000, pp. 490-5.
    Platz EA, Kawachi I, Rimm EB, et al. Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study. J Urol. 2000;163(2):490-5.
    Platz, E. A., Kawachi, I., Rimm, E. B., Willett, W. C., & Giovannucci, E. (2000). Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study. The Journal of Urology, 163(2), pp. 490-5.
    Platz EA, et al. Race, Ethnicity and Benign Prostatic Hyperplasia in the Health Professionals Follow-up Study. J Urol. 2000;163(2):490-5. PubMed PMID: 10647663.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study. AU - Platz,E A, AU - Kawachi,I, AU - Rimm,E B, AU - Willett,W C, AU - Giovannucci,E, PY - 2000/1/27/pubmed PY - 2000/1/27/medline PY - 2000/1/27/entrez SP - 490 EP - 5 JF - The Journal of urology JO - J. Urol. VL - 163 IS - 2 N2 - PURPOSE: We examined whether the prevalence of benign prostatic hyperplasia (BPH) varies by racial or ethnic origin in a large cohort of American male health professionals. MATERIALS AND METHODS: Included in our study were 1,508 men who underwent surgery for BPH between 1986 and 1994, and 1,837 with high moderate to severe lower urinary tract symptoms assessed by the American Urological Association symptom index in 1992 or 1994. "Noncases" comprised 23,246 asymptomatic participants. Self-reported major ancestry was black in 201 men, Asian in 413, other origin in 604 and white in 25,373. White heritage was further classified as southern European in 6,408 men, Scandinavian in 2,951 and other white in 16,014. The relative risk of BPH and 95% confidence intervals (CI) adjusted for age, body mass index, alcohol consumption, smoking and physical activity were calculated by logistic regression. RESULTS: Black men were not at increased risk for BPH (relative risk 0.85, 95% CI 0.55 to 1.31) compared with white men. Asian men were less likely to have undergone BPH surgery (relative risk 0.41, 95% CI 0.21 to 0.82), although the relative risk for symptoms was similar to that of white men. White men whose major ancestry was southern European were at modestly higher risk for BPH surgery (relative risk 1.28, 95% CI 1.12 to 1.46) and symptoms (relative risk 1.34, 95% CI 1.20 to 1.50), whereas men of Scandinavian heritage were at slightly decreased risk for symptoms than those of other white heritages. CONCLUSIONS: Racial and ethnic variation is evident in the incidence of BPH surgery and symptom severity. Whether this observed variation reflects underlying biological phenomena rather than differences in symptom tolerance requires further exploration. SN - 0022-5347 UR - https://www.unboundmedicine.com/medline/citation/10647663/Race_ethnicity_and_benign_prostatic_hyperplasia_in_the_health_professionals_follow_up_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-5347(05)67909-8 DB - PRIME DP - Unbound Medicine ER -