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A clinical comparison of SIDS and explained sudden infant deaths: how healthy and how normal? CESDI SUDI Research Group. Confidential Inquiry into Stillbirths and Deaths in Infancy study.
Arch Dis Child. 2000 Feb; 82(2):98-106.AD

Abstract

OBJECTIVES

To compare the clinical characteristics associated with sudden infant death syndrome (SIDS) and explained sudden unexpected deaths in infancy (SUDI).

DESIGN

Three year population based, case control study with parental interviews for each death and four age matched controls.

SETTING

Five regions in England (population, > 17 million; live births, > 470,000).

SUBJECTS

SIDS: 325 infants; explained SUDI: 72 infants; controls: 1,588 infants.

RESULTS

In the univariate analysis, all the clinical features and health markers at birth, after discharge from hospital, during life, and shortly before death, significant among the infants with SIDS were in the same direction among the infants who died of explained SUDI. In the multivariate analysis, at least one apparent life threatening event had been experienced by more of the infants who died than in controls (SIDS: 12% v 3% controls; odds ratio (OR) = 2.55; 95% confidence interval (CI), 1.02 to 6.41; explained SUDI: 15% v 4% controls; OR = 16.81; 95% CI, 2.52 to 112.30). Using a retrospective illness scoring system based on "Baby Check", both index groups showed significant markers of illness in the last 24 hours (SIDS: 22% v 8% controls; OR = 4.17; 95% CI, 1.88 to 9.24; explained SUDI: 49% v 8% controls; OR = 31.20; 95% CI, 6.93 to 140.5).

CONCLUSIONS

The clinical characteristics of SIDS and explained SUDI are similar. Baby Check might help identify seriously ill babies at risk of sudden death, particularly in high risk infants.

Authors+Show Affiliations

Newcastle Neonatal Service, Ward 35, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10648361

Citation

Platt, M W., et al. "A Clinical Comparison of SIDS and Explained Sudden Infant Deaths: How Healthy and How Normal? CESDI SUDI Research Group. Confidential Inquiry Into Stillbirths and Deaths in Infancy Study." Archives of Disease in Childhood, vol. 82, no. 2, 2000, pp. 98-106.
Platt MW, Blair PS, Fleming PJ, et al. A clinical comparison of SIDS and explained sudden infant deaths: how healthy and how normal? CESDI SUDI Research Group. Confidential Inquiry into Stillbirths and Deaths in Infancy study. Arch Dis Child. 2000;82(2):98-106.
Platt, M. W., Blair, P. S., Fleming, P. J., Smith, I. J., Cole, T. J., Leach, C. E., Berry, P. J., & Golding, J. (2000). A clinical comparison of SIDS and explained sudden infant deaths: how healthy and how normal? CESDI SUDI Research Group. Confidential Inquiry into Stillbirths and Deaths in Infancy study. Archives of Disease in Childhood, 82(2), 98-106.
Platt MW, et al. A Clinical Comparison of SIDS and Explained Sudden Infant Deaths: How Healthy and How Normal? CESDI SUDI Research Group. Confidential Inquiry Into Stillbirths and Deaths in Infancy Study. Arch Dis Child. 2000;82(2):98-106. PubMed PMID: 10648361.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A clinical comparison of SIDS and explained sudden infant deaths: how healthy and how normal? CESDI SUDI Research Group. Confidential Inquiry into Stillbirths and Deaths in Infancy study. AU - Platt,M W, AU - Blair,P S, AU - Fleming,P J, AU - Smith,I J, AU - Cole,T J, AU - Leach,C E, AU - Berry,P J, AU - Golding,J, PY - 2000/1/29/pubmed PY - 2000/3/4/medline PY - 2000/1/29/entrez SP - 98 EP - 106 JF - Archives of disease in childhood JO - Arch. Dis. Child. VL - 82 IS - 2 N2 - OBJECTIVES: To compare the clinical characteristics associated with sudden infant death syndrome (SIDS) and explained sudden unexpected deaths in infancy (SUDI). DESIGN: Three year population based, case control study with parental interviews for each death and four age matched controls. SETTING: Five regions in England (population, > 17 million; live births, > 470,000). SUBJECTS: SIDS: 325 infants; explained SUDI: 72 infants; controls: 1,588 infants. RESULTS: In the univariate analysis, all the clinical features and health markers at birth, after discharge from hospital, during life, and shortly before death, significant among the infants with SIDS were in the same direction among the infants who died of explained SUDI. In the multivariate analysis, at least one apparent life threatening event had been experienced by more of the infants who died than in controls (SIDS: 12% v 3% controls; odds ratio (OR) = 2.55; 95% confidence interval (CI), 1.02 to 6.41; explained SUDI: 15% v 4% controls; OR = 16.81; 95% CI, 2.52 to 112.30). Using a retrospective illness scoring system based on "Baby Check", both index groups showed significant markers of illness in the last 24 hours (SIDS: 22% v 8% controls; OR = 4.17; 95% CI, 1.88 to 9.24; explained SUDI: 49% v 8% controls; OR = 31.20; 95% CI, 6.93 to 140.5). CONCLUSIONS: The clinical characteristics of SIDS and explained SUDI are similar. Baby Check might help identify seriously ill babies at risk of sudden death, particularly in high risk infants. SN - 1468-2044 UR - https://www.unboundmedicine.com/medline/citation/10648361/A_clinical_comparison_of_SIDS_and_explained_sudden_infant_deaths:_how_healthy_and_how_normal_CESDI_SUDI_Research_Group__Confidential_Inquiry_into_Stillbirths_and_Deaths_in_Infancy_study_ L2 - http://adc.bmj.com/cgi/pmidlookup?view=long&pmid=10648361 DB - PRIME DP - Unbound Medicine ER -