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Folate and vitamin B12-deficiency anemias in Vietnamese immigrants living in Southern California.
South Med J. 2000 Jan; 93(1):53-7.SM

Abstract

BACKGROUND

Although the occurrence of iron deficiency anemia and hemoglobinopathies in Vietnamese immigrants has been reported, folate and vitamin B12 deficiencies have not. Proper diagnosis and effective treatment is necessary to achieve a complete correction of anemia.

METHODS

We retrospectively analyzed the records of Vietnamese immigrants seen in our medical clinic from 1991 to 1993. Fifty-nine anemic patients (48 females and 11 males) had low levels of red blood cell (RBC) folate and/or serum vitamin B12.

RESULTS

The patients' mean age was 37.7+/-17 years. Mean hemoglobin and hematocrit values were 11.4+/-0.7 g/dL and 34.4%+/-2.2%, respectively. Mean corpuscular volume (MCV) was normal in 40 patients (68%) (mean, 89.1+/-5 fL) and low in 19 patients (32%) (mean, 69.7+/-6 fL). Forty-four patients had low RBC folate levels (mean, 157.7+/-41.7 ng/mL). Twenty patients had low serum vitamin B12 levels (mean, 165.6+/-47 pg/mL). Fourteen patients had ferritin levels of <20%.

CONCLUSIONS

Concomitant folate, vitamin B12, and iron deficiencies or hemoglobinopathies might have been responsible for either normal or low MCV in some of our anemic patients. In this ethnic group, RBC folate and serum vitamin B12 levels should be determined in all anemic patients.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10653066

Citation

Luong, K V., and L T. Nguyen. "Folate and Vitamin B12-deficiency Anemias in Vietnamese Immigrants Living in Southern California." Southern Medical Journal, vol. 93, no. 1, 2000, pp. 53-7.
Luong KV, Nguyen LT. Folate and vitamin B12-deficiency anemias in Vietnamese immigrants living in Southern California. South Med J. 2000;93(1):53-7.
Luong, K. V., & Nguyen, L. T. (2000). Folate and vitamin B12-deficiency anemias in Vietnamese immigrants living in Southern California. Southern Medical Journal, 93(1), 53-7.
Luong KV, Nguyen LT. Folate and Vitamin B12-deficiency Anemias in Vietnamese Immigrants Living in Southern California. South Med J. 2000;93(1):53-7. PubMed PMID: 10653066.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Folate and vitamin B12-deficiency anemias in Vietnamese immigrants living in Southern California. AU - Luong,K V, AU - Nguyen,L T, PY - 2000/2/1/pubmed PY - 2000/2/1/medline PY - 2000/2/1/entrez SP - 53 EP - 7 JF - Southern medical journal JO - South. Med. J. VL - 93 IS - 1 N2 - BACKGROUND: Although the occurrence of iron deficiency anemia and hemoglobinopathies in Vietnamese immigrants has been reported, folate and vitamin B12 deficiencies have not. Proper diagnosis and effective treatment is necessary to achieve a complete correction of anemia. METHODS: We retrospectively analyzed the records of Vietnamese immigrants seen in our medical clinic from 1991 to 1993. Fifty-nine anemic patients (48 females and 11 males) had low levels of red blood cell (RBC) folate and/or serum vitamin B12. RESULTS: The patients' mean age was 37.7+/-17 years. Mean hemoglobin and hematocrit values were 11.4+/-0.7 g/dL and 34.4%+/-2.2%, respectively. Mean corpuscular volume (MCV) was normal in 40 patients (68%) (mean, 89.1+/-5 fL) and low in 19 patients (32%) (mean, 69.7+/-6 fL). Forty-four patients had low RBC folate levels (mean, 157.7+/-41.7 ng/mL). Twenty patients had low serum vitamin B12 levels (mean, 165.6+/-47 pg/mL). Fourteen patients had ferritin levels of <20%. CONCLUSIONS: Concomitant folate, vitamin B12, and iron deficiencies or hemoglobinopathies might have been responsible for either normal or low MCV in some of our anemic patients. In this ethnic group, RBC folate and serum vitamin B12 levels should be determined in all anemic patients. SN - 0038-4348 UR - https://www.unboundmedicine.com/medline/citation/10653066/Folate_and_vitamin_B12_deficiency_anemias_in_Vietnamese_immigrants_living_in_Southern_California_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=10653066.ui DB - PRIME DP - Unbound Medicine ER -