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Antimicrobial activity of home disinfectants and natural products against potential human pathogens.
Infect Control Hosp Epidemiol. 2000 Jan; 21(1):33-8.IC

Abstract

OBJECTIVE

To assess the efficacy of both natural products (vinegar, baking soda) and common commercial disinfectants (Vesphene IIse, TBQ, Clorox, Lysol Disinfectant Spray, Lysol Antibacterial Kitchen Cleaner, Mr. Clean Ultra, ethanol) designed for home or institutional use against potential human pathogens, including selected antibiotic-resistant bacteria.

DESIGN

A quantitative suspension test was used to assess the efficacy of selected disinfectants following exposure times of 30 seconds and 5 minutes. Activity was assessed against Staphylococcus aureus, Salmonella choleraesuis, Escherichia coli O157:H7, and Pseudomonas aeruginosa. Selected disinfectants were also tested against poliovirus, vancomycin-susceptible and -resistant Enterococcus species, and methicillin-susceptible and -resistant S. aureus.

RESULTS

The following compounds demonstrated excellent antimicrobial activity (>5.6-8.2 log10 reduction) at both exposure times: TBQ, Vesphene, Clorox, ethanol, and Lysol Antibacterial Kitchen Cleaner. Mr. Clean eliminated 4 to >6 logs10 and Lysol Disinfectant approximately 4 logs10 of pathogenic microorganisms at both exposure times. Vinegar eliminated <3 logs10 of S. aureus and E. coli, and baking soda <3 logs10 of all test pathogens. All tested chemical disinfectants completely inactivated both antibiotic-resistant and -susceptible bacteria at both exposure times. Only two disinfectants, Clorox and Lysol, demonstrated excellent activity (>3 log10 reduction) against poliovirus.

CONCLUSIONS

A variety of commercial household disinfectants were highly effective against potential bacterial pathogens. The natural products were less effective than commercial household disinfectants. Only Clorox and Lysol disinfectant were effective against poliovirus.

Authors+Show Affiliations

University of North Carolina, School of Medicine, Department of Hospital Epidemiology, UNC Hospitals, 27599-7030, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10656352

Citation

Rutala, W A., et al. "Antimicrobial Activity of Home Disinfectants and Natural Products Against Potential Human Pathogens." Infection Control and Hospital Epidemiology, vol. 21, no. 1, 2000, pp. 33-8.
Rutala WA, Barbee SL, Aguiar NC, et al. Antimicrobial activity of home disinfectants and natural products against potential human pathogens. Infect Control Hosp Epidemiol. 2000;21(1):33-8.
Rutala, W. A., Barbee, S. L., Aguiar, N. C., Sobsey, M. D., & Weber, D. J. (2000). Antimicrobial activity of home disinfectants and natural products against potential human pathogens. Infection Control and Hospital Epidemiology, 21(1), 33-8.
Rutala WA, et al. Antimicrobial Activity of Home Disinfectants and Natural Products Against Potential Human Pathogens. Infect Control Hosp Epidemiol. 2000;21(1):33-8. PubMed PMID: 10656352.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activity of home disinfectants and natural products against potential human pathogens. AU - Rutala,W A, AU - Barbee,S L, AU - Aguiar,N C, AU - Sobsey,M D, AU - Weber,D J, PY - 2000/2/3/pubmed PY - 2000/2/26/medline PY - 2000/2/3/entrez SP - 33 EP - 8 JF - Infection control and hospital epidemiology JO - Infect Control Hosp Epidemiol VL - 21 IS - 1 N2 - OBJECTIVE: To assess the efficacy of both natural products (vinegar, baking soda) and common commercial disinfectants (Vesphene IIse, TBQ, Clorox, Lysol Disinfectant Spray, Lysol Antibacterial Kitchen Cleaner, Mr. Clean Ultra, ethanol) designed for home or institutional use against potential human pathogens, including selected antibiotic-resistant bacteria. DESIGN: A quantitative suspension test was used to assess the efficacy of selected disinfectants following exposure times of 30 seconds and 5 minutes. Activity was assessed against Staphylococcus aureus, Salmonella choleraesuis, Escherichia coli O157:H7, and Pseudomonas aeruginosa. Selected disinfectants were also tested against poliovirus, vancomycin-susceptible and -resistant Enterococcus species, and methicillin-susceptible and -resistant S. aureus. RESULTS: The following compounds demonstrated excellent antimicrobial activity (>5.6-8.2 log10 reduction) at both exposure times: TBQ, Vesphene, Clorox, ethanol, and Lysol Antibacterial Kitchen Cleaner. Mr. Clean eliminated 4 to >6 logs10 and Lysol Disinfectant approximately 4 logs10 of pathogenic microorganisms at both exposure times. Vinegar eliminated <3 logs10 of S. aureus and E. coli, and baking soda <3 logs10 of all test pathogens. All tested chemical disinfectants completely inactivated both antibiotic-resistant and -susceptible bacteria at both exposure times. Only two disinfectants, Clorox and Lysol, demonstrated excellent activity (>3 log10 reduction) against poliovirus. CONCLUSIONS: A variety of commercial household disinfectants were highly effective against potential bacterial pathogens. The natural products were less effective than commercial household disinfectants. Only Clorox and Lysol disinfectant were effective against poliovirus. SN - 0899-823X UR - https://www.unboundmedicine.com/medline/citation/10656352/full_citation L2 - https://www.cambridge.org/core/product/identifier/ICHE6896/type/journal_article DB - PRIME DP - Unbound Medicine ER -