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Diphtheria in Lithuania, 1986-1996.
J Infect Dis. 2000 Feb; 181 Suppl 1:S55-9.JI

Abstract

Diphtheria reappeared in Lithuania in 1986 and rose to epidemic levels by 1992. Between 1991 and 1996, 110 cases of diphtheria were registered, with an incidence of 0.03-1.15/100,000 population. Most cases (84%) and all 17 deaths occurred among persons >/=15 years, most of whom had never been vaccinated. Persons 40-49 years old had the highest average annual age-specific morbidity (1.70/100,000) and mortality (0.53/100,000) rates. Low levels of immunity among individuals 40-49 years old and migration to epidemic areas in Russia and Belarus contributed to the epidemic's occurrence. Between 1991 and 1995, toxigenic Corynebacterium diphtheriae strains were isolated from 84 of all registered patients (76%), and nontoxigenic strains were isolated from 13 (12%). By 1996, two mass vaccination campaigns, which provided one dose of vaccine to individuals 25-30 years old and three doses of vaccine to persons 31-60 years old, helped reduce the number of cases. The first campaign achieved 69% coverage; the second achieved 48% coverage.

Authors+Show Affiliations

Center of Pediatrics, Vilnius University, LT 2009 Vilnius, Lithuania (Lietuva). usonis@ktl.mii.ltNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10657191

Citation

Usonis, V, et al. "Diphtheria in Lithuania, 1986-1996." The Journal of Infectious Diseases, vol. 181 Suppl 1, 2000, pp. S55-9.
Usonis V, Bakasenas V, Morkunas B, et al. Diphtheria in Lithuania, 1986-1996. J Infect Dis. 2000;181 Suppl 1:S55-9.
Usonis, V., Bakasenas, V., Morkunas, B., Valentelis, R., Ching, P., & Kreysler, J. (2000). Diphtheria in Lithuania, 1986-1996. The Journal of Infectious Diseases, 181 Suppl 1, S55-9.
Usonis V, et al. Diphtheria in Lithuania, 1986-1996. J Infect Dis. 2000;181 Suppl 1:S55-9. PubMed PMID: 10657191.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diphtheria in Lithuania, 1986-1996. AU - Usonis,V, AU - Bakasenas,V, AU - Morkunas,B, AU - Valentelis,R, AU - Ching,P, AU - Kreysler,J, PY - 2000/2/5/pubmed PY - 2000/4/15/medline PY - 2000/2/5/entrez SP - S55 EP - 9 JF - The Journal of infectious diseases JO - J. Infect. Dis. VL - 181 Suppl 1 N2 - Diphtheria reappeared in Lithuania in 1986 and rose to epidemic levels by 1992. Between 1991 and 1996, 110 cases of diphtheria were registered, with an incidence of 0.03-1.15/100,000 population. Most cases (84%) and all 17 deaths occurred among persons >/=15 years, most of whom had never been vaccinated. Persons 40-49 years old had the highest average annual age-specific morbidity (1.70/100,000) and mortality (0.53/100,000) rates. Low levels of immunity among individuals 40-49 years old and migration to epidemic areas in Russia and Belarus contributed to the epidemic's occurrence. Between 1991 and 1995, toxigenic Corynebacterium diphtheriae strains were isolated from 84 of all registered patients (76%), and nontoxigenic strains were isolated from 13 (12%). By 1996, two mass vaccination campaigns, which provided one dose of vaccine to individuals 25-30 years old and three doses of vaccine to persons 31-60 years old, helped reduce the number of cases. The first campaign achieved 69% coverage; the second achieved 48% coverage. SN - 0022-1899 UR - https://www.unboundmedicine.com/medline/citation/10657191/Diphtheria_in_Lithuania_1986_1996_ L2 - https://academic.oup.com/jid/article-lookup/doi/10.1086/315539 DB - PRIME DP - Unbound Medicine ER -