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[Sickle cell anemia and pregnancy: review of 68 cases in Guadeloupe].
J Gynecol Obstet Biol Reprod (Paris). 2000 Feb; 29(1):86-93.JG

Abstract

Pregnancy in women with major sickle cell syndromes is a high risk maternofetal situation. This descriptive study presents the features and the clinical course of 68 pregnancies in sickle cell women who were delivered in Guadeloupe from January 1(st) 1993 to December 31(st) 1997. Specific complications were observed in all hemoglobin types, but with a severer course in SS women. Painful vaso-occlusive crises were the main causes of hospitalisation (88% of SS pregnancies and 27% of SC pregnancies) associated most often with worsening anemia and / or infection. Acute chest syndrome was observed in all genotypes at any time throughout pregnancy and during the post partum period. One death occurred (a 16 years old SBeta(+)thal woman). Fetal mortality and morbidity were also high, intrauterine growth retardation and fetal death being the most frequent fetal complications. The rates of prematurity (21%) and caesarean section (48%) were higher than in the whole population. Three (3) neonatal deaths occurred. A multidisciplinary and specific approach, vigilance of health care providers and patient compliance are required to manage efficiently pregnancy, delivery and post partum in sickle cell women.

Authors+Show Affiliations

Centre Caribéen de Drépanocytose(CCD) " Guy Mérault ", 97159 Pointe-à-Pitre, Cedex Guadeloupe.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

fre

PubMed ID

10675838

Citation

Leborgne-Samuel, Y, et al. "[Sickle Cell Anemia and Pregnancy: Review of 68 Cases in Guadeloupe]." Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction, vol. 29, no. 1, 2000, pp. 86-93.
Leborgne-Samuel Y, Janky E, Venditelli F, et al. [Sickle cell anemia and pregnancy: review of 68 cases in Guadeloupe]. J Gynecol Obstet Biol Reprod (Paris). 2000;29(1):86-93.
Leborgne-Samuel, Y., Janky, E., Venditelli, F., Salin, J., Daijardin, J. B., Couchy, B., Etienne-Julan, M., & Berchel, C. (2000). [Sickle cell anemia and pregnancy: review of 68 cases in Guadeloupe]. Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction, 29(1), 86-93.
Leborgne-Samuel Y, et al. [Sickle Cell Anemia and Pregnancy: Review of 68 Cases in Guadeloupe]. J Gynecol Obstet Biol Reprod (Paris). 2000;29(1):86-93. PubMed PMID: 10675838.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Sickle cell anemia and pregnancy: review of 68 cases in Guadeloupe]. AU - Leborgne-Samuel,Y, AU - Janky,E, AU - Venditelli,F, AU - Salin,J, AU - Daijardin,J B, AU - Couchy,B, AU - Etienne-Julan,M, AU - Berchel,C, PY - 2000/2/17/pubmed PY - 2000/3/25/medline PY - 2000/2/17/entrez SP - 86 EP - 93 JF - Journal de gynecologie, obstetrique et biologie de la reproduction JO - J Gynecol Obstet Biol Reprod (Paris) VL - 29 IS - 1 N2 - Pregnancy in women with major sickle cell syndromes is a high risk maternofetal situation. This descriptive study presents the features and the clinical course of 68 pregnancies in sickle cell women who were delivered in Guadeloupe from January 1(st) 1993 to December 31(st) 1997. Specific complications were observed in all hemoglobin types, but with a severer course in SS women. Painful vaso-occlusive crises were the main causes of hospitalisation (88% of SS pregnancies and 27% of SC pregnancies) associated most often with worsening anemia and / or infection. Acute chest syndrome was observed in all genotypes at any time throughout pregnancy and during the post partum period. One death occurred (a 16 years old SBeta(+)thal woman). Fetal mortality and morbidity were also high, intrauterine growth retardation and fetal death being the most frequent fetal complications. The rates of prematurity (21%) and caesarean section (48%) were higher than in the whole population. Three (3) neonatal deaths occurred. A multidisciplinary and specific approach, vigilance of health care providers and patient compliance are required to manage efficiently pregnancy, delivery and post partum in sickle cell women. SN - 0368-2315 UR - https://www.unboundmedicine.com/medline/citation/10675838/[Sickle_cell_anemia_and_pregnancy:_review_of_68_cases_in_Guadeloupe]_ L2 - http://www.em-consulte.com/retrieve/pii/MDOI-JGYN-02-2000-29-1-0368-2315-101019-ART12 DB - PRIME DP - Unbound Medicine ER -