Tags

Type your tag names separated by a space and hit enter

[Nutritional effects of glutamine-enriched parenteral nutrition on transplanted small intestine in the rat].
Zhonghua Wai Ke Za Zhi. 1997 Sep; 35(9):558-60.ZW

Abstract

We evaluated the preventive effects of glutamine-enriched pareneral nutrition on the atrophy and hypofunction of the transplanted small intestines in the rat. Wistar rats received jejunal isografts and central venous catheters for parenteral nutrition (PN) for ten days. Rats received either PN with 3% alanyl-glutamine or the PN with isonitrogenous ballanced nonessential amino acids. Glutamine-enriched PN significantly increased mucosal villous height mucosal thickness, crypt depth and villous surface area compared with the non-glutamine PN. Normal enterocyte ultrastructure of the graft was maintained in the Glutamine-enriched group. Atrophied microvilli and broken mitochondrial crista were observed in the control group. It was found that the amount of absorption of 15N-glycine was greater at the 1st, 2nd, 3rd hour in glutamine-enriched group than that in the control. These results indicate that the glutamine-enriched parenteral nutrition can promote the proliferation of mucosa, maintain the ultrastructure and improve the amino acid absorption in the transplanted small bowel in the rat.

Authors+Show Affiliations

Department of General Surgery, Zhongshan Hospital, Shanghai Medical University.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

10678035

Citation

Zhang, H, et al. "[Nutritional Effects of Glutamine-enriched Parenteral Nutrition On Transplanted Small Intestine in the Rat]." Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], vol. 35, no. 9, 1997, pp. 558-60.
Zhang H, Wu Z, Zhang Y. [Nutritional effects of glutamine-enriched parenteral nutrition on transplanted small intestine in the rat]. Zhonghua Wai Ke Za Zhi. 1997;35(9):558-60.
Zhang, H., Wu, Z., & Zhang, Y. (1997). [Nutritional effects of glutamine-enriched parenteral nutrition on transplanted small intestine in the rat]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], 35(9), 558-60.
Zhang H, Wu Z, Zhang Y. [Nutritional Effects of Glutamine-enriched Parenteral Nutrition On Transplanted Small Intestine in the Rat]. Zhonghua Wai Ke Za Zhi. 1997;35(9):558-60. PubMed PMID: 10678035.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Nutritional effects of glutamine-enriched parenteral nutrition on transplanted small intestine in the rat]. AU - Zhang,H, AU - Wu,Z, AU - Zhang,Y, PY - 2000/3/4/pubmed PY - 2000/3/4/medline PY - 2000/3/4/entrez SP - 558 EP - 60 JF - Zhonghua wai ke za zhi [Chinese journal of surgery] JO - Zhonghua Wai Ke Za Zhi VL - 35 IS - 9 N2 - We evaluated the preventive effects of glutamine-enriched pareneral nutrition on the atrophy and hypofunction of the transplanted small intestines in the rat. Wistar rats received jejunal isografts and central venous catheters for parenteral nutrition (PN) for ten days. Rats received either PN with 3% alanyl-glutamine or the PN with isonitrogenous ballanced nonessential amino acids. Glutamine-enriched PN significantly increased mucosal villous height mucosal thickness, crypt depth and villous surface area compared with the non-glutamine PN. Normal enterocyte ultrastructure of the graft was maintained in the Glutamine-enriched group. Atrophied microvilli and broken mitochondrial crista were observed in the control group. It was found that the amount of absorption of 15N-glycine was greater at the 1st, 2nd, 3rd hour in glutamine-enriched group than that in the control. These results indicate that the glutamine-enriched parenteral nutrition can promote the proliferation of mucosa, maintain the ultrastructure and improve the amino acid absorption in the transplanted small bowel in the rat. SN - 0529-5815 UR - https://www.unboundmedicine.com/medline/citation/10678035/[Nutritional_effects_of_glutamine_enriched_parenteral_nutrition_on_transplanted_small_intestine_in_the_rat]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=0529-5815&year=1997&vol=35&issue=9&fpage=558 DB - PRIME DP - Unbound Medicine ER -