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Plasmodium infection-induced changes in salivary gland proteins of malaria vector Anopheles stephensi (Diptera:Culicidae).
Jpn J Infect Dis. 1999 Oct; 52(5):214-6.JJ

Abstract

Parasitism by Plasmodium yoelii yoelii induced 18 polypeptides in the salivary glands of aging malaria vector Anopheles stephensi. A polypeptide of low molecular size (30 kDa) could generally be induced at all infected stages. On day 5 post blood feeding (PBF), no new polypeptide could be found in the salivary glands. Seven polypeptides of low molecular size and 3 of high molecular size could be induced on day 11 PBF, which inducibility coincided with the invasion of the salivary glands by the sporozoites. Quantitatively, soluble proteins decreased in the salivary glands by about one-third in females that had consumed infected or uninfected blood meal on day 9 (oocysts stage) as compared to nonfeeding females. However, on day 15, in the salivary glands invaded by sporozoites, the amount of proteins obtained from infected females was approximately 26% lower than that obtained from uninfected females. A similar reduction was also observed in aged (20 days PBF) salivary glands of infected mosquitoes. These proteins could confer parasite tolerance to the females and enhance parasite transmission potential.

Authors+Show Affiliations

Department of Biosciences, Maharshi Dayanand University, Haryana, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10680088

Citation

Shandilya, H, et al. "Plasmodium Infection-induced Changes in Salivary Gland Proteins of Malaria Vector Anopheles Stephensi (Diptera:Culicidae)." Japanese Journal of Infectious Diseases, vol. 52, no. 5, 1999, pp. 214-6.
Shandilya H, Gakhar SK, Adak T. Plasmodium infection-induced changes in salivary gland proteins of malaria vector Anopheles stephensi (Diptera:Culicidae). Jpn J Infect Dis. 1999;52(5):214-6.
Shandilya, H., Gakhar, S. K., & Adak, T. (1999). Plasmodium infection-induced changes in salivary gland proteins of malaria vector Anopheles stephensi (Diptera:Culicidae). Japanese Journal of Infectious Diseases, 52(5), 214-6.
Shandilya H, Gakhar SK, Adak T. Plasmodium Infection-induced Changes in Salivary Gland Proteins of Malaria Vector Anopheles Stephensi (Diptera:Culicidae). Jpn J Infect Dis. 1999;52(5):214-6. PubMed PMID: 10680088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasmodium infection-induced changes in salivary gland proteins of malaria vector Anopheles stephensi (Diptera:Culicidae). AU - Shandilya,H, AU - Gakhar,S K, AU - Adak,T, PY - 2000/2/19/pubmed PY - 2000/3/11/medline PY - 2000/2/19/entrez SP - 214 EP - 6 JF - Japanese journal of infectious diseases JO - Jpn. J. Infect. Dis. VL - 52 IS - 5 N2 - Parasitism by Plasmodium yoelii yoelii induced 18 polypeptides in the salivary glands of aging malaria vector Anopheles stephensi. A polypeptide of low molecular size (30 kDa) could generally be induced at all infected stages. On day 5 post blood feeding (PBF), no new polypeptide could be found in the salivary glands. Seven polypeptides of low molecular size and 3 of high molecular size could be induced on day 11 PBF, which inducibility coincided with the invasion of the salivary glands by the sporozoites. Quantitatively, soluble proteins decreased in the salivary glands by about one-third in females that had consumed infected or uninfected blood meal on day 9 (oocysts stage) as compared to nonfeeding females. However, on day 15, in the salivary glands invaded by sporozoites, the amount of proteins obtained from infected females was approximately 26% lower than that obtained from uninfected females. A similar reduction was also observed in aged (20 days PBF) salivary glands of infected mosquitoes. These proteins could confer parasite tolerance to the females and enhance parasite transmission potential. SN - 1344-6304 UR - https://www.unboundmedicine.com/medline/citation/10680088/Plasmodium_infection_induced_changes_in_salivary_gland_proteins_of_malaria_vector_Anopheles_stephensi__Diptera:Culicidae__ L2 - http://www.diseaseinfosearch.org/result/4415 DB - PRIME DP - Unbound Medicine ER -