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A diet high in whole and unrefined foods favorably alters lipids, antioxidant defenses, and colon function.

Abstract

OBJECTIVE

Diets rich in whole and unrefined foods, like whole grains, dark green and yellow/orange-fleshed vegetables and fruits, legumes, nuts and seeds, contain high concentrations of antioxidant phenolics, fibers and numerous other phytochemicals that may be protective against chronic diseases. This study compared the effects of a phytochemical-rich diet versus a refined-food diet on lipoproteins, antioxidant defenses and colon function.

METHODS

Twelve hyperlipidemic women followed two diets for four weeks starting with a refined-food diet. Subjects then directly crossed over to the phytochemical-rich diet. Duplicate, fasting serum lipids and single, fasting antioxidant enzymes were measured at the end of the four-week refined-food diet period (baseline) and again at the end of the phytochemical-rich diet period.

RESULTS

Total energy and total fat intake were similar during both diet periods, but there was a decrease in saturated fat (SFA) of 61% in the phytochemical-rich diet group. Dietary fiber, vitamin E, vitamin C and carotene intakes were 160%, 145%, 160% and 500% more, respectively, than during the refined-food diet period. The phytochemical-rich diet induced a drop of 13% in total cholesterol (TC) (p < 0.05) and 16% (p < 0.001) in low density lipoprotein-cholesterol (LDL-C). Erythrocyte superoxide dismutase decreased 69% (p < 0.01) and glutathione peroxidase dropped 35% (p < 0.01). Colon function was improved on the phytochemical-rich diet.

CONCLUSIONS

A diet abundant in phytochemically-rich foods beneficially affected lipoproteins, decreased need for oxidative defense mechanisms and improved colon function.

Authors+Show Affiliations

,

Sphera Foundation, Los Altos, California 94023, USA.

, ,

Source

MeSH

Adolescent
Adult
Antioxidants
Ascorbic Acid
Carotenoids
Colon
Diet
Dietary Fats
Dietary Fiber
Edible Grain
Energy Intake
Female
Food
Fruit
Glutathione Peroxidase
Humans
Lipids
Superoxide Dismutase
Vegetables
Vitamin E

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10682877

Citation

Bruce, B, et al. "A Diet High in Whole and Unrefined Foods Favorably Alters Lipids, Antioxidant Defenses, and Colon Function." Journal of the American College of Nutrition, vol. 19, no. 1, 2000, pp. 61-7.
Bruce B, Spiller GA, Klevay LM, et al. A diet high in whole and unrefined foods favorably alters lipids, antioxidant defenses, and colon function. J Am Coll Nutr. 2000;19(1):61-7.
Bruce, B., Spiller, G. A., Klevay, L. M., & Gallagher, S. K. (2000). A diet high in whole and unrefined foods favorably alters lipids, antioxidant defenses, and colon function. Journal of the American College of Nutrition, 19(1), pp. 61-7.
Bruce B, et al. A Diet High in Whole and Unrefined Foods Favorably Alters Lipids, Antioxidant Defenses, and Colon Function. J Am Coll Nutr. 2000;19(1):61-7. PubMed PMID: 10682877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A diet high in whole and unrefined foods favorably alters lipids, antioxidant defenses, and colon function. AU - Bruce,B, AU - Spiller,G A, AU - Klevay,L M, AU - Gallagher,S K, PY - 2000/2/22/pubmed PY - 2000/3/4/medline PY - 2000/2/22/entrez SP - 61 EP - 7 JF - Journal of the American College of Nutrition JO - J Am Coll Nutr VL - 19 IS - 1 N2 - OBJECTIVE: Diets rich in whole and unrefined foods, like whole grains, dark green and yellow/orange-fleshed vegetables and fruits, legumes, nuts and seeds, contain high concentrations of antioxidant phenolics, fibers and numerous other phytochemicals that may be protective against chronic diseases. This study compared the effects of a phytochemical-rich diet versus a refined-food diet on lipoproteins, antioxidant defenses and colon function. METHODS: Twelve hyperlipidemic women followed two diets for four weeks starting with a refined-food diet. Subjects then directly crossed over to the phytochemical-rich diet. Duplicate, fasting serum lipids and single, fasting antioxidant enzymes were measured at the end of the four-week refined-food diet period (baseline) and again at the end of the phytochemical-rich diet period. RESULTS: Total energy and total fat intake were similar during both diet periods, but there was a decrease in saturated fat (SFA) of 61% in the phytochemical-rich diet group. Dietary fiber, vitamin E, vitamin C and carotene intakes were 160%, 145%, 160% and 500% more, respectively, than during the refined-food diet period. The phytochemical-rich diet induced a drop of 13% in total cholesterol (TC) (p < 0.05) and 16% (p < 0.001) in low density lipoprotein-cholesterol (LDL-C). Erythrocyte superoxide dismutase decreased 69% (p < 0.01) and glutathione peroxidase dropped 35% (p < 0.01). Colon function was improved on the phytochemical-rich diet. CONCLUSIONS: A diet abundant in phytochemically-rich foods beneficially affected lipoproteins, decreased need for oxidative defense mechanisms and improved colon function. SN - 0731-5724 UR - https://www.unboundmedicine.com/medline/citation/10682877/A_diet_high_in_whole_and_unrefined_foods_favorably_alters_lipids_antioxidant_defenses_and_colon_function_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -