Tags

Type your tag names separated by a space and hit enter

Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on diet and cancer.
Cancer Causes Control 2000; 11(2):101-15CC

Abstract

OBJECTIVE

The purpose was to study the association between vegetable and fruit consumption and lung cancer incidence using 1074 cases after 6.3 years of follow-up in the Netherlands Cohort Study.

METHODS

Dietary intake was assessed using a 150-item food-frequency questionnaire. Multivariate models were used including age, sex, family history of lung cancer, highest educational level attained, and smoking history.

RESULTS

Statistically significant inverse associations were found with total vegetables and most vegetable groups. Rate ratios (RRs) based on consumption frequency showed the strongest effect of vegetables from the Brassica group (RR 0.5, 95% confidence interval (95% CI) 0.3-0.9, for consumption > or = 3 times per week versus < or = once a month). RR of highest versus lowest quintile of total vegetable consumption was 0.7 (95% CI 0.5-1.0, p-trend 0.001). Statistically significant inverse associations were found for all fruits listed in the questionnaire. RRs for quintiles of total fruit intake were 1.0, 0.7, 0.6, 0.6 and 0.8 respectively (p-trend < 0.0001). Protective effects of fruits and vegetables were stronger in current than in former smokers, and weaker for adenocarcinomas than for other types of tumors.

CONCLUSIONS

Inverse associations with lung cancer are found for both vegetable and fruit intake, but no specific type of vegetable or fruit seems to be particularly responsible.

Authors+Show Affiliations

Department of Nutritional Epidemiology, TNO Nutrition and Food Research Institute, Zeist, The Netherlands. Voorrips@voeding.tno.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10710193

Citation

Voorrips, L E., et al. "Vegetable and Fruit Consumption and Lung Cancer Risk in the Netherlands Cohort Study On Diet and Cancer." Cancer Causes & Control : CCC, vol. 11, no. 2, 2000, pp. 101-15.
Voorrips LE, Goldbohm RA, Verhoeven DT, et al. Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on diet and cancer. Cancer Causes Control. 2000;11(2):101-15.
Voorrips, L. E., Goldbohm, R. A., Verhoeven, D. T., van Poppel, G. A., Sturmans, F., Hermus, R. J., & van den Brandt, P. A. (2000). Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on diet and cancer. Cancer Causes & Control : CCC, 11(2), pp. 101-15.
Voorrips LE, et al. Vegetable and Fruit Consumption and Lung Cancer Risk in the Netherlands Cohort Study On Diet and Cancer. Cancer Causes Control. 2000;11(2):101-15. PubMed PMID: 10710193.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on diet and cancer. AU - Voorrips,L E, AU - Goldbohm,R A, AU - Verhoeven,D T, AU - van Poppel,G A, AU - Sturmans,F, AU - Hermus,R J, AU - van den Brandt,P A, PY - 2000/3/10/pubmed PY - 2000/4/1/medline PY - 2000/3/10/entrez SP - 101 EP - 15 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 11 IS - 2 N2 - OBJECTIVE: The purpose was to study the association between vegetable and fruit consumption and lung cancer incidence using 1074 cases after 6.3 years of follow-up in the Netherlands Cohort Study. METHODS: Dietary intake was assessed using a 150-item food-frequency questionnaire. Multivariate models were used including age, sex, family history of lung cancer, highest educational level attained, and smoking history. RESULTS: Statistically significant inverse associations were found with total vegetables and most vegetable groups. Rate ratios (RRs) based on consumption frequency showed the strongest effect of vegetables from the Brassica group (RR 0.5, 95% confidence interval (95% CI) 0.3-0.9, for consumption > or = 3 times per week versus < or = once a month). RR of highest versus lowest quintile of total vegetable consumption was 0.7 (95% CI 0.5-1.0, p-trend 0.001). Statistically significant inverse associations were found for all fruits listed in the questionnaire. RRs for quintiles of total fruit intake were 1.0, 0.7, 0.6, 0.6 and 0.8 respectively (p-trend < 0.0001). Protective effects of fruits and vegetables were stronger in current than in former smokers, and weaker for adenocarcinomas than for other types of tumors. CONCLUSIONS: Inverse associations with lung cancer are found for both vegetable and fruit intake, but no specific type of vegetable or fruit seems to be particularly responsible. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/10710193/Vegetable_and_fruit_consumption_and_lung_cancer_risk_in_the_Netherlands_Cohort_Study_on_diet_and_cancer_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=10710193.ui DB - PRIME DP - Unbound Medicine ER -