Tags

Type your tag names separated by a space and hit enter

Usefulness of screening program for celiac disease in autoimmune thyroiditis.

Abstract

We determined the prevalence of celiac disease in subjects with autoimmune thyroiditis compared with sick and healthy subjects. The screening was performed with IgA-class endomysium antibody, by indirect immunofluorescence using human umbilical cord as the antigenic substrate. Six of the 172 patients with autoimmune thyroiditis were found to be anti-endomysium positive (3.4%) and five of these underwent intestinal biopsy, which showed total villous atrophy. By contrast, 3 (0.75%) of 396 patients with nongastroenterologic malignancies and 10 (0.25%) of 4000 blood donors were found to have celiac disease. The prevalence of autoimmune diseases was significantly higher in patients with both celiac disease and autoimmune thyroiditis than in patients with autoimmune thyroiditis alone (P = 0.01). This study confirms that celiac disease is increased among patients with autoimmune thyroiditis. We suggest that these patients may benefit from screening for celiac disease so as to eliminate symptoms and limit the risk of developing other autoimmune disorders.

Links

  • Aggregator Full Text
  • Authors+Show Affiliations

    ,

    Clinica Pediatrica, I.R.C.C.S. Burlo Garofolo, Trieste, Italy.

    , , , , , , ,

    Source

    Digestive diseases and sciences 45:2 2000 Feb pg 403-6

    MeSH

    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Antibodies
    Celiac Disease
    Female
    Fluorescent Antibody Technique, Indirect
    Humans
    Male
    Mass Screening
    Middle Aged
    Sensitivity and Specificity
    Thyroiditis, Autoimmune

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    10711459

    Citation

    Berti, I, et al. "Usefulness of Screening Program for Celiac Disease in Autoimmune Thyroiditis." Digestive Diseases and Sciences, vol. 45, no. 2, 2000, pp. 403-6.
    Berti I, Trevisiol C, Tommasini A, et al. Usefulness of screening program for celiac disease in autoimmune thyroiditis. Dig Dis Sci. 2000;45(2):403-6.
    Berti, I., Trevisiol, C., Tommasini, A., Città, A., Neri, E., Geatti, O., ... Not, T. (2000). Usefulness of screening program for celiac disease in autoimmune thyroiditis. Digestive Diseases and Sciences, 45(2), pp. 403-6.
    Berti I, et al. Usefulness of Screening Program for Celiac Disease in Autoimmune Thyroiditis. Dig Dis Sci. 2000;45(2):403-6. PubMed PMID: 10711459.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Usefulness of screening program for celiac disease in autoimmune thyroiditis. AU - Berti,I, AU - Trevisiol,C, AU - Tommasini,A, AU - Città,A, AU - Neri,E, AU - Geatti,O, AU - Giammarini,A, AU - Ventura,A, AU - Not,T, PY - 2000/3/11/pubmed PY - 2000/3/25/medline PY - 2000/3/11/entrez SP - 403 EP - 6 JF - Digestive diseases and sciences JO - Dig. Dis. Sci. VL - 45 IS - 2 N2 - We determined the prevalence of celiac disease in subjects with autoimmune thyroiditis compared with sick and healthy subjects. The screening was performed with IgA-class endomysium antibody, by indirect immunofluorescence using human umbilical cord as the antigenic substrate. Six of the 172 patients with autoimmune thyroiditis were found to be anti-endomysium positive (3.4%) and five of these underwent intestinal biopsy, which showed total villous atrophy. By contrast, 3 (0.75%) of 396 patients with nongastroenterologic malignancies and 10 (0.25%) of 4000 blood donors were found to have celiac disease. The prevalence of autoimmune diseases was significantly higher in patients with both celiac disease and autoimmune thyroiditis than in patients with autoimmune thyroiditis alone (P = 0.01). This study confirms that celiac disease is increased among patients with autoimmune thyroiditis. We suggest that these patients may benefit from screening for celiac disease so as to eliminate symptoms and limit the risk of developing other autoimmune disorders. SN - 0163-2116 UR - https://www.unboundmedicine.com/medline/citation/10711459/full_citation L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=10711459.ui DB - PRIME DP - Unbound Medicine ER -