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[Uveitis associated with zoster sine herpete. Diagnosis and clinical findings].
Nippon Ganka Gakkai Zasshi. 2000 Feb; 104(2):97-102.NG

Abstract

PURPOSE

Zoster sine herpete (ZSH) causes solely neurologic symptoms without the eruption that is evident in herpes zoster ophthalmicus. It is occasionally complicated by acute granulomatous uveitis. We examined patients suspected of ZSH for detection of the varicella-zoster virus (VZV) genome, and discussed its clinical appearance.

MATERIALS AND METHODS

Nine patients were presumed to have ZSH. All manifested acute granulomatous iridocyclitis and high intraocular pressure without eruption. A polymerase chain reaction (PCR) analysis of the aqueous humor was performed.

RESULTS

Five patients were positive for VZV DNA. They showed mutton-fat keratic precipitates and high intraocular pressure in the early stage. Pigmentation in the anterior chamber angle, pigmented keratic precipitates, and finally sectoral iris atrophy were observed in the recovery stage. These clinical findings were common to ZSH.

CONCLUSIONS

The ocular lesions in ZSH were shown to have distinctive characteristics, and PCR is useful to determine etiological agents in the early stage of disease.

Authors+Show Affiliations

Department of Ophthalmology, Tokyo Medical University, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

10714158

Citation

Kashiwase, M, et al. "[Uveitis Associated With Zoster Sine Herpete. Diagnosis and Clinical Findings]." Nippon Ganka Gakkai Zasshi, vol. 104, no. 2, 2000, pp. 97-102.
Kashiwase M, Sakai J, Usui M. [Uveitis associated with zoster sine herpete. Diagnosis and clinical findings]. Nippon Ganka Gakkai Zasshi. 2000;104(2):97-102.
Kashiwase, M., Sakai, J., & Usui, M. (2000). [Uveitis associated with zoster sine herpete. Diagnosis and clinical findings]. Nippon Ganka Gakkai Zasshi, 104(2), 97-102.
Kashiwase M, Sakai J, Usui M. [Uveitis Associated With Zoster Sine Herpete. Diagnosis and Clinical Findings]. Nippon Ganka Gakkai Zasshi. 2000;104(2):97-102. PubMed PMID: 10714158.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Uveitis associated with zoster sine herpete. Diagnosis and clinical findings]. AU - Kashiwase,M, AU - Sakai,J, AU - Usui,M, PY - 2000/3/14/pubmed PY - 2000/6/8/medline PY - 2000/3/14/entrez SP - 97 EP - 102 JF - Nippon Ganka Gakkai zasshi JO - Nippon Ganka Gakkai Zasshi VL - 104 IS - 2 N2 - PURPOSE: Zoster sine herpete (ZSH) causes solely neurologic symptoms without the eruption that is evident in herpes zoster ophthalmicus. It is occasionally complicated by acute granulomatous uveitis. We examined patients suspected of ZSH for detection of the varicella-zoster virus (VZV) genome, and discussed its clinical appearance. MATERIALS AND METHODS: Nine patients were presumed to have ZSH. All manifested acute granulomatous iridocyclitis and high intraocular pressure without eruption. A polymerase chain reaction (PCR) analysis of the aqueous humor was performed. RESULTS: Five patients were positive for VZV DNA. They showed mutton-fat keratic precipitates and high intraocular pressure in the early stage. Pigmentation in the anterior chamber angle, pigmented keratic precipitates, and finally sectoral iris atrophy were observed in the recovery stage. These clinical findings were common to ZSH. CONCLUSIONS: The ocular lesions in ZSH were shown to have distinctive characteristics, and PCR is useful to determine etiological agents in the early stage of disease. SN - 0029-0203 UR - https://www.unboundmedicine.com/medline/citation/10714158/[Uveitis_associated_with_zoster_sine_herpete__Diagnosis_and_clinical_findings]_ L2 - http://www.diseaseinfosearch.org/result/9684 DB - PRIME DP - Unbound Medicine ER -
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