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RETRACTED ARTICLE

Walnuts lower serum cholesterol in Japanese men and women.
J Nutr. 2000 Feb; 130(2):171-6.JN

Abstract

Recent studies have shown that incorporating moderate quantities of walnuts into the recommended cholesterol-lowering diet in the U.S. decreased serum concentrations of total cholesterol in normal American men. To explore whether walnut consumption would also prove effective as part of the Japanese diet, we studied the effects of walnut consumption on serum lipids and blood pressure in Japanese subjects. We randomly assigned 20 men and 20 women to two mixed natural diets, each to be consumed for 4 wk in a crossover design. Both diets conformed to the average Japanese diet (reference diet) and contained identical foods and macronutrients, except that 12.5% of the energy of the walnut diet was derived from walnuts (43-57 g/d) (offset by lesser amounts of fatty foods, meat and visible fat). Total cholesterol concentration was 0.16 mmol/L lower for men (P = 0.05) and 0.21 mmol/L lower for women (P<0.01) when they consumed the walnut diet than when they consumed the reference diet. The LDL cholesterol concentrations were 0.18 mmol/L lower for men (P = 0.13) and 0.22 mmol/L lower for women (P<0.01) when they consumed the walnut diet. The ratio of LDL cholesterol to HDL cholesterol and the apolipoprotein B concentration were also lowered by the walnut diet (P<0.05). Blood pressures did not differ between the walnut and reference diet periods. Incorporating moderate quantities of walnuts into the average Japanese diet while maintaining the intake of total dietary fat and energy decreases serum total cholesterol concentrations and favorably modifies the lipoprotein profile in Japanese, particularly in women.

Authors+Show Affiliations

Laboratory of Nutrition Chemistry, Division of Bioresource and Bioenvironmental Sciences, Graduate School, Kyushu University, Fukuoka, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Retracted Publication

Language

eng

PubMed ID

10720165

Citation

Iwamoto, M, et al. "Walnuts Lower Serum Cholesterol in Japanese Men and Women." The Journal of Nutrition, vol. 130, no. 2, 2000, pp. 171-6.
Iwamoto M, Sato M, Kono M, et al. Walnuts lower serum cholesterol in Japanese men and women. J Nutr. 2000;130(2):171-6.
Iwamoto, M., Sato, M., Kono, M., Hirooka, Y., Sakai, K., Takeshita, A., & Imaizumi, K. (2000). Walnuts lower serum cholesterol in Japanese men and women. The Journal of Nutrition, 130(2), 171-6.
Iwamoto M, et al. Walnuts Lower Serum Cholesterol in Japanese Men and Women. J Nutr. 2000;130(2):171-6. PubMed PMID: 10720165.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Walnuts lower serum cholesterol in Japanese men and women. AU - Iwamoto,M, AU - Sato,M, AU - Kono,M, AU - Hirooka,Y, AU - Sakai,K, AU - Takeshita,A, AU - Imaizumi,K, PY - 2000/3/17/pubmed PY - 2000/4/1/medline PY - 2000/3/17/entrez SP - 171 EP - 6 JF - The Journal of nutrition JO - J Nutr VL - 130 IS - 2 N2 - Recent studies have shown that incorporating moderate quantities of walnuts into the recommended cholesterol-lowering diet in the U.S. decreased serum concentrations of total cholesterol in normal American men. To explore whether walnut consumption would also prove effective as part of the Japanese diet, we studied the effects of walnut consumption on serum lipids and blood pressure in Japanese subjects. We randomly assigned 20 men and 20 women to two mixed natural diets, each to be consumed for 4 wk in a crossover design. Both diets conformed to the average Japanese diet (reference diet) and contained identical foods and macronutrients, except that 12.5% of the energy of the walnut diet was derived from walnuts (43-57 g/d) (offset by lesser amounts of fatty foods, meat and visible fat). Total cholesterol concentration was 0.16 mmol/L lower for men (P = 0.05) and 0.21 mmol/L lower for women (P<0.01) when they consumed the walnut diet than when they consumed the reference diet. The LDL cholesterol concentrations were 0.18 mmol/L lower for men (P = 0.13) and 0.22 mmol/L lower for women (P<0.01) when they consumed the walnut diet. The ratio of LDL cholesterol to HDL cholesterol and the apolipoprotein B concentration were also lowered by the walnut diet (P<0.05). Blood pressures did not differ between the walnut and reference diet periods. Incorporating moderate quantities of walnuts into the average Japanese diet while maintaining the intake of total dietary fat and energy decreases serum total cholesterol concentrations and favorably modifies the lipoprotein profile in Japanese, particularly in women. SN - 0022-3166 UR - https://www.unboundmedicine.com/medline/citation/10720165/Walnuts_lower_serum_cholesterol_in_Japanese_men_and_women_ L2 - https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/130.2.171 DB - PRIME DP - Unbound Medicine ER -