Tags

Type your tag names separated by a space and hit enter

Meta-analysis of studies on breast cancer risk and diet: the role of fruit and vegetable consumption and the intake of associated micronutrients.
Eur J Cancer 2000; 36(5):636-46EJ

Abstract

A meta-analysis was carried out, in order to summarise published data on the relationship between breast cancer, fruit and vegetable consumption and/or the intake of beta-carotene and vitamin C. Relative risks were extracted from 26 published studies from 1982 to 1997. Random and fixed effects models were used. Between studies, heterogeneity was found for vegetables, fruit, vitamin C but not for beta-carotene. Summary relative risk (RR) estimates based upon a random effects model, except for beta-carotene, for 'high consumption' compared with 'low consumption', derived from the studies satisfying the inclusion criteria were as follows: vegetable consumption: RR=0.75 (95% CI (confidence interval) 0.66-0.85) from 17 studies; fruit consumption: RR=0.94 (95% CI 0.79-1.11) from 12 studies; vitamin C: RR=0.80 (95% CI 0.68-0.95) from 9 studies; beta-carotene: RR=0.82 (95% CI 0.76-0.91) from 11 studies. This analysis confirms the association between intake of vegetables and, to a lesser extent, fruits and breast cancer risk from published sources. Increasing vegetable consumption might reduce the risk of breast cancer.

Authors+Show Affiliations

Division of Epidemiology and Biostatics, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy. sara.gandini@ieo.itNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10738129

Citation

Gandini, S, et al. "Meta-analysis of Studies On Breast Cancer Risk and Diet: the Role of Fruit and Vegetable Consumption and the Intake of Associated Micronutrients." European Journal of Cancer (Oxford, England : 1990), vol. 36, no. 5, 2000, pp. 636-46.
Gandini S, Merzenich H, Robertson C, et al. Meta-analysis of studies on breast cancer risk and diet: the role of fruit and vegetable consumption and the intake of associated micronutrients. Eur J Cancer. 2000;36(5):636-46.
Gandini, S., Merzenich, H., Robertson, C., & Boyle, P. (2000). Meta-analysis of studies on breast cancer risk and diet: the role of fruit and vegetable consumption and the intake of associated micronutrients. European Journal of Cancer (Oxford, England : 1990), 36(5), pp. 636-46.
Gandini S, et al. Meta-analysis of Studies On Breast Cancer Risk and Diet: the Role of Fruit and Vegetable Consumption and the Intake of Associated Micronutrients. Eur J Cancer. 2000;36(5):636-46. PubMed PMID: 10738129.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Meta-analysis of studies on breast cancer risk and diet: the role of fruit and vegetable consumption and the intake of associated micronutrients. AU - Gandini,S, AU - Merzenich,H, AU - Robertson,C, AU - Boyle,P, PY - 2000/3/30/pubmed PY - 2000/6/10/medline PY - 2000/3/30/entrez SP - 636 EP - 46 JF - European journal of cancer (Oxford, England : 1990) JO - Eur. J. Cancer VL - 36 IS - 5 N2 - A meta-analysis was carried out, in order to summarise published data on the relationship between breast cancer, fruit and vegetable consumption and/or the intake of beta-carotene and vitamin C. Relative risks were extracted from 26 published studies from 1982 to 1997. Random and fixed effects models were used. Between studies, heterogeneity was found for vegetables, fruit, vitamin C but not for beta-carotene. Summary relative risk (RR) estimates based upon a random effects model, except for beta-carotene, for 'high consumption' compared with 'low consumption', derived from the studies satisfying the inclusion criteria were as follows: vegetable consumption: RR=0.75 (95% CI (confidence interval) 0.66-0.85) from 17 studies; fruit consumption: RR=0.94 (95% CI 0.79-1.11) from 12 studies; vitamin C: RR=0.80 (95% CI 0.68-0.95) from 9 studies; beta-carotene: RR=0.82 (95% CI 0.76-0.91) from 11 studies. This analysis confirms the association between intake of vegetables and, to a lesser extent, fruits and breast cancer risk from published sources. Increasing vegetable consumption might reduce the risk of breast cancer. SN - 0959-8049 UR - https://www.unboundmedicine.com/medline/citation/10738129/Meta_analysis_of_studies_on_breast_cancer_risk_and_diet:_the_role_of_fruit_and_vegetable_consumption_and_the_intake_of_associated_micronutrients_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0959804900000228 DB - PRIME DP - Unbound Medicine ER -