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[Urinary excretion of porphyrins and their precursors. Longterm observations in acute intermittent porphyrias (author's transl)].
MMW Munch Med Wochenschr. 1979 Mar 30; 121(13):457-8.MM

Abstract

On the basis of many years of examination and supervision of 26 patients with acute intermittent porphyria three different types of excretion behavior in the urine can be distinguished. 1. After porphyric crises the urinary porphyrin content is completely normalized. 2. Even after the crisis the excretion levels for porphyrins remain very high. 3. The urinary porphyrins return to normal levels but the increases in precursors such as delta-aminolevulinic acid and porphobilinogen still persist. 4. In the diagnosis true acute coproporphyria and increased of excretion of precursors must be differentiated as well as increased coproporphyrin resulting from liver diseases, exogenic, toxic influences and secondary disorders of porphyrin metabolism.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

107424

Citation

Brugsch, J, and H Müller. "[Urinary Excretion of Porphyrins and Their Precursors. Longterm Observations in Acute Intermittent Porphyrias (author's Transl)]." MMW, Munchener Medizinische Wochenschrift, vol. 121, no. 13, 1979, pp. 457-8.
Brugsch J, Müller H. [Urinary excretion of porphyrins and their precursors. Longterm observations in acute intermittent porphyrias (author's transl)]. MMW Munch Med Wochenschr. 1979;121(13):457-8.
Brugsch, J., & Müller, H. (1979). [Urinary excretion of porphyrins and their precursors. Longterm observations in acute intermittent porphyrias (author's transl)]. MMW, Munchener Medizinische Wochenschrift, 121(13), 457-8.
Brugsch J, Müller H. [Urinary Excretion of Porphyrins and Their Precursors. Longterm Observations in Acute Intermittent Porphyrias (author's Transl)]. MMW Munch Med Wochenschr. 1979 Mar 30;121(13):457-8. PubMed PMID: 107424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Urinary excretion of porphyrins and their precursors. Longterm observations in acute intermittent porphyrias (author's transl)]. AU - Brugsch,J, AU - Müller,H, PY - 1979/3/30/pubmed PY - 1979/3/30/medline PY - 1979/3/30/entrez SP - 457 EP - 8 JF - MMW, Munchener medizinische Wochenschrift JO - MMW Munch Med Wochenschr VL - 121 IS - 13 N2 - On the basis of many years of examination and supervision of 26 patients with acute intermittent porphyria three different types of excretion behavior in the urine can be distinguished. 1. After porphyric crises the urinary porphyrin content is completely normalized. 2. Even after the crisis the excretion levels for porphyrins remain very high. 3. The urinary porphyrins return to normal levels but the increases in precursors such as delta-aminolevulinic acid and porphobilinogen still persist. 4. In the diagnosis true acute coproporphyria and increased of excretion of precursors must be differentiated as well as increased coproporphyrin resulting from liver diseases, exogenic, toxic influences and secondary disorders of porphyrin metabolism. SN - 0341-3098 UR - https://www.unboundmedicine.com/medline/citation/107424/[Urinary_excretion_of_porphyrins_and_their_precursors__Longterm_observations_in_acute_intermittent_porphyrias__author's_transl_]_ L2 - https://medlineplus.gov/porphyria.html DB - PRIME DP - Unbound Medicine ER -