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Poor predictive ability of urinalysis and microscopic examination to detect urinary tract infection.
Am J Clin Pathol. 2000 May; 113(5):709-13.AJ

Abstract

Results of urinalysis, particularly the leukocyte esterase and nitrite tests, often are used to determine whether treatment is needed or a culture will be performed in cases of suspected urinary tract infection. However, there is disagreement over the quality of urinalysis as a screening test for urinary tract infections. Final urine culture results (n = 225) were obtained from the clinical microbiology laboratory. Stepwise binary logistic regression was used to derive a model using presence of infection as determined by culture as the dependent variable and urinalysis results as independent variables. A second set of data (n = 128) then was obtained to test the model. Statistical significance and the ability to predict infection based on urinalysis results were determined. Results indicated a lack of sensitivity for leukocyte esterase, nitrite, and presence of bacteria in the microscopic examination as indicators of urinary tract infection.

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Authors+Show Affiliations

Van Nostrand JD
Medical University of South Carolina, Charleston 29425, USA.
Junkins AD
No affiliation info available
Bartholdi RK
No affiliation info available

MeSH

Carboxylic Ester HydrolasesFemaleHumansLogistic ModelsMaleNitritesOdds RatioSensitivity and SpecificityUrinalysisUrinary Tract InfectionsUrine

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10800404

Citation

Van Nostrand, J D., et al. "Poor Predictive Ability of Urinalysis and Microscopic Examination to Detect Urinary Tract Infection." American Journal of Clinical Pathology, vol. 113, no. 5, 2000, pp. 709-13.
Van Nostrand JD, Junkins AD, Bartholdi RK. Poor predictive ability of urinalysis and microscopic examination to detect urinary tract infection. Am J Clin Pathol. 2000;113(5):709-13.
Van Nostrand, J. D., Junkins, A. D., & Bartholdi, R. K. (2000). Poor predictive ability of urinalysis and microscopic examination to detect urinary tract infection. American Journal of Clinical Pathology, 113(5), 709-13.
Van Nostrand JD, Junkins AD, Bartholdi RK. Poor Predictive Ability of Urinalysis and Microscopic Examination to Detect Urinary Tract Infection. Am J Clin Pathol. 2000;113(5):709-13. PubMed PMID: 10800404.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Poor predictive ability of urinalysis and microscopic examination to detect urinary tract infection. AU - Van Nostrand,J D, AU - Junkins,A D, AU - Bartholdi,R K, PY - 2000/5/9/pubmed PY - 2000/5/20/medline PY - 2000/5/9/entrez SP - 709 EP - 13 JF - American journal of clinical pathology JO - Am J Clin Pathol VL - 113 IS - 5 N2 - Results of urinalysis, particularly the leukocyte esterase and nitrite tests, often are used to determine whether treatment is needed or a culture will be performed in cases of suspected urinary tract infection. However, there is disagreement over the quality of urinalysis as a screening test for urinary tract infections. Final urine culture results (n = 225) were obtained from the clinical microbiology laboratory. Stepwise binary logistic regression was used to derive a model using presence of infection as determined by culture as the dependent variable and urinalysis results as independent variables. A second set of data (n = 128) then was obtained to test the model. Statistical significance and the ability to predict infection based on urinalysis results were determined. Results indicated a lack of sensitivity for leukocyte esterase, nitrite, and presence of bacteria in the microscopic examination as indicators of urinary tract infection. SN - 0002-9173 UR - https://www.unboundmedicine.com/medline/citation/10800404/Poor_predictive_ability_of_urinalysis_and_microscopic_examination_to_detect_urinary_tract_infection_ L2 - https://academic.oup.com/ajcp/article-lookup/doi/10.1309/428N-60XK-UQ3Q-BXLC DB - PRIME DP - Unbound Medicine ER -