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[Protein concentration of perilymph in guinea pigs after noise exposure].
Acta Otolaryngol. 1975 Jul-Aug; 80(1-2):32-7.AO

Abstract

The protein concentration in the perilymph of noise-exposed guinea pigs was investigated using a micromethod described previously. The animals were exposed to wide band noise at 140 dB for one hour unilaterally in a closed acoustic system. Perilymph was obtained after exposure at different intervals: immediately, 6 or 24 hours later. From animals exposed to noise, it is particularly more difficult to obtain perilymph without blood contamination than from normal ones. Even post mortem, it is difficult to obtain samples without blood contamination and without hemolysis, particularly from the scala tympani. Therefore, some animals were perfused intra-arterially with Ringer solution or with Infukoll M 40 before decapitation. After exposure to noise only a small increase in protein concentration of the perilymph can be detected in the noise-exposed ears of animals perfused intra-arterially. The difference in concentration is most distinct in samples extracted 6 hours after noise exposure had ceased. No reliable clue to the source of this protein could be obtained from these investigations.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

1080944

Citation

Scheibe, F, et al. "[Protein Concentration of Perilymph in Guinea Pigs After Noise Exposure]." Acta Oto-laryngologica, vol. 80, no. 1-2, 1975, pp. 32-7.
Scheibe F, Hache U, Haupt H, et al. [Protein concentration of perilymph in guinea pigs after noise exposure]. Acta Otolaryngol. 1975;80(1-2):32-7.
Scheibe, F., Hache, U., Haupt, H., & Gerhardt, H. J. (1975). [Protein concentration of perilymph in guinea pigs after noise exposure]. Acta Oto-laryngologica, 80(1-2), 32-7.
Scheibe F, et al. [Protein Concentration of Perilymph in Guinea Pigs After Noise Exposure]. Acta Otolaryngol. 1975 Jul-Aug;80(1-2):32-7. PubMed PMID: 1080944.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Protein concentration of perilymph in guinea pigs after noise exposure]. AU - Scheibe,F, AU - Hache,U, AU - Haupt,H, AU - Gerhardt,H J, PY - 1975/7/1/pubmed PY - 1975/7/1/medline PY - 1975/7/1/entrez SP - 32 EP - 7 JF - Acta oto-laryngologica JO - Acta Otolaryngol VL - 80 IS - 1-2 N2 - The protein concentration in the perilymph of noise-exposed guinea pigs was investigated using a micromethod described previously. The animals were exposed to wide band noise at 140 dB for one hour unilaterally in a closed acoustic system. Perilymph was obtained after exposure at different intervals: immediately, 6 or 24 hours later. From animals exposed to noise, it is particularly more difficult to obtain perilymph without blood contamination than from normal ones. Even post mortem, it is difficult to obtain samples without blood contamination and without hemolysis, particularly from the scala tympani. Therefore, some animals were perfused intra-arterially with Ringer solution or with Infukoll M 40 before decapitation. After exposure to noise only a small increase in protein concentration of the perilymph can be detected in the noise-exposed ears of animals perfused intra-arterially. The difference in concentration is most distinct in samples extracted 6 hours after noise exposure had ceased. No reliable clue to the source of this protein could be obtained from these investigations. SN - 0001-6489 UR - https://www.unboundmedicine.com/medline/citation/1080944/[Protein_concentration_of_perilymph_in_guinea_pigs_after_noise_exposure]_ L2 - https://medlineplus.gov/noise.html DB - PRIME DP - Unbound Medicine ER -