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Human papillomavirus in head and neck carcinomas: prevalence, physical status and relationship with clinical/pathological parameters.
Anticancer Res. 2000 Mar-Apr; 20(2B):1301-5.AR

Abstract

The association of human papillomavirus (HPV) infection to head and neck squamous cell carcinomas was evaluated in 66 patients affected by tumours of the oral cavity (n = 38), the tonsil (n = 4), the pharynx (n = 2), and the larynx (n = 22). HPV DNA was detected by PCR-based assays, recognizing late and early genes. Twenty-four cases were HPV infected (36.4%), mostly by high and/or intermediate risk types. HPV 16 was integrated in 7/12 positive tumours without site-specificity. HPV infection was not related to age, gender, tumour stage, differentiation grade, and use of alcohol and/or tobacco. The findings indicate that HPV infection may be related to a proportion of head and neck carcinomas but its association is not as clear as that found in cervical cancer.

Authors+Show Affiliations

Laboratory of Virology, Regina Elena Cancer Institute, Rome, Italy. badaracco@crs.ifo.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10810439

Citation

Badaracco, G, et al. "Human Papillomavirus in Head and Neck Carcinomas: Prevalence, Physical Status and Relationship With Clinical/pathological Parameters." Anticancer Research, vol. 20, no. 2B, 2000, pp. 1301-5.
Badaracco G, Venuti A, Morello R, et al. Human papillomavirus in head and neck carcinomas: prevalence, physical status and relationship with clinical/pathological parameters. Anticancer Res. 2000;20(2B):1301-5.
Badaracco, G., Venuti, A., Morello, R., Muller, A., & Marcante, M. L. (2000). Human papillomavirus in head and neck carcinomas: prevalence, physical status and relationship with clinical/pathological parameters. Anticancer Research, 20(2B), 1301-5.
Badaracco G, et al. Human Papillomavirus in Head and Neck Carcinomas: Prevalence, Physical Status and Relationship With Clinical/pathological Parameters. Anticancer Res. 2000;20(2B):1301-5. PubMed PMID: 10810439.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Human papillomavirus in head and neck carcinomas: prevalence, physical status and relationship with clinical/pathological parameters. AU - Badaracco,G, AU - Venuti,A, AU - Morello,R, AU - Muller,A, AU - Marcante,M L, PY - 2000/5/16/pubmed PY - 2000/6/3/medline PY - 2000/5/16/entrez SP - 1301 EP - 5 JF - Anticancer research JO - Anticancer Res. VL - 20 IS - 2B N2 - The association of human papillomavirus (HPV) infection to head and neck squamous cell carcinomas was evaluated in 66 patients affected by tumours of the oral cavity (n = 38), the tonsil (n = 4), the pharynx (n = 2), and the larynx (n = 22). HPV DNA was detected by PCR-based assays, recognizing late and early genes. Twenty-four cases were HPV infected (36.4%), mostly by high and/or intermediate risk types. HPV 16 was integrated in 7/12 positive tumours without site-specificity. HPV infection was not related to age, gender, tumour stage, differentiation grade, and use of alcohol and/or tobacco. The findings indicate that HPV infection may be related to a proportion of head and neck carcinomas but its association is not as clear as that found in cervical cancer. SN - 0250-7005 UR - https://www.unboundmedicine.com/medline/citation/10810439/Human_papillomavirus_in_head_and_neck_carcinomas:_prevalence_physical_status_and_relationship_with_clinical/pathological_parameters_ L2 - https://medlineplus.gov/headandneckcancer.html DB - PRIME DP - Unbound Medicine ER -