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Twin studies in schizophrenia with special emphasis on concordance figures.
Am J Med Genet 2000; 97(1):4-11AJ

Abstract

Twin studies in schizophrenia have been reviewed with special emphasis on concordance rates in population-based investigations. Sources of error have been discussed with particular focus on sampling. The pair-wise concordance rates in schizophrenia are 30-40% in MZ and 5-10% in DZ, with somewhat higher rates for proband concordance. The findings from twin studies support the diathesis stress model in schizophrenia, and it is argued that the polygenic model gives the best explanation for the empirical findings.

Authors+Show Affiliations

Department of Psychiatry, University of Oslo, Oslo, Norway. einar.kringlen@psykiatri.uio.no

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

10813799

Citation

Kringlen, E. "Twin Studies in Schizophrenia With Special Emphasis On Concordance Figures." American Journal of Medical Genetics, vol. 97, no. 1, 2000, pp. 4-11.
Kringlen E. Twin studies in schizophrenia with special emphasis on concordance figures. Am J Med Genet. 2000;97(1):4-11.
Kringlen, E. (2000). Twin studies in schizophrenia with special emphasis on concordance figures. American Journal of Medical Genetics, 97(1), pp. 4-11.
Kringlen E. Twin Studies in Schizophrenia With Special Emphasis On Concordance Figures. Am J Med Genet. 2000;97(1):4-11. PubMed PMID: 10813799.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Twin studies in schizophrenia with special emphasis on concordance figures. A1 - Kringlen,E, PY - 2000/5/17/pubmed PY - 2003/4/4/medline PY - 2000/5/17/entrez SP - 4 EP - 11 JF - American journal of medical genetics JO - Am. J. Med. Genet. VL - 97 IS - 1 N2 - Twin studies in schizophrenia have been reviewed with special emphasis on concordance rates in population-based investigations. Sources of error have been discussed with particular focus on sampling. The pair-wise concordance rates in schizophrenia are 30-40% in MZ and 5-10% in DZ, with somewhat higher rates for proband concordance. The findings from twin studies support the diathesis stress model in schizophrenia, and it is argued that the polygenic model gives the best explanation for the empirical findings. SN - 0148-7299 UR - https://www.unboundmedicine.com/medline/citation/10813799/full_citation L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0148-7299&date=2000&volume=97&issue=1&spage=4 DB - PRIME DP - Unbound Medicine ER -