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[Digestive tract hemorrhages of cirrhotic patients. Relation between hepatic insufficiency and the hemorrhagic lesion].
Nouv Presse Med. 1975 Dec 06; 4(42):2993-6.NP

Abstract

The cause of upper gastrointestinal bleeding was studied in 85 cirrhotic patients by emergency endoscopy. In every patient, one or several lesions were observed and the site of bleeding was ascertained in 59. The two main causes were oesophago-gastric varices (46 p.cent) and acute mucosal lesions(42 p.cent). The source of bleeding appeared to be related to the degree of liver function impairment. In patients with no or moderate liver function impariment, bleeding usually originated from varices or from drug-associated mucosal erosions. Patients with severe impairment of liver function most often bled from spontaneous acute oeso-gastro-duodenal ulcerations. These ulcerations resembled what has been described in "stress" hemorrhage. Because of the relationship between liver function and the cause of hemorrhage, mortality was lower in variceal bleeders (29 p.cent) than in patients with spontaneous ulcerations (83 p.cent). In patients with severely impaired liver function, portacaval shunt was rarely indicated since hemorrhage was generally due to acute mucosal ulcerations.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

1083014

Citation

Franco, D, et al. "[Digestive Tract Hemorrhages of Cirrhotic Patients. Relation Between Hepatic Insufficiency and the Hemorrhagic Lesion]." La Nouvelle Presse Medicale, vol. 4, no. 42, 1975, pp. 2993-6.
Franco D, Deporte A, Darragon T, et al. [Digestive tract hemorrhages of cirrhotic patients. Relation between hepatic insufficiency and the hemorrhagic lesion]. Nouv Presse Med. 1975;4(42):2993-6.
Franco, D., Deporte, A., Darragon, T., & Bismuth, H. (1975). [Digestive tract hemorrhages of cirrhotic patients. Relation between hepatic insufficiency and the hemorrhagic lesion]. La Nouvelle Presse Medicale, 4(42), 2993-6.
Franco D, et al. [Digestive Tract Hemorrhages of Cirrhotic Patients. Relation Between Hepatic Insufficiency and the Hemorrhagic Lesion]. Nouv Presse Med. 1975 Dec 6;4(42):2993-6. PubMed PMID: 1083014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Digestive tract hemorrhages of cirrhotic patients. Relation between hepatic insufficiency and the hemorrhagic lesion]. AU - Franco,D, AU - Deporte,A, AU - Darragon,T, AU - Bismuth,H, PY - 1975/12/6/pubmed PY - 1975/12/6/medline PY - 1975/12/6/entrez SP - 2993 EP - 6 JF - La Nouvelle presse medicale JO - Nouv Presse Med VL - 4 IS - 42 N2 - The cause of upper gastrointestinal bleeding was studied in 85 cirrhotic patients by emergency endoscopy. In every patient, one or several lesions were observed and the site of bleeding was ascertained in 59. The two main causes were oesophago-gastric varices (46 p.cent) and acute mucosal lesions(42 p.cent). The source of bleeding appeared to be related to the degree of liver function impairment. In patients with no or moderate liver function impariment, bleeding usually originated from varices or from drug-associated mucosal erosions. Patients with severe impairment of liver function most often bled from spontaneous acute oeso-gastro-duodenal ulcerations. These ulcerations resembled what has been described in "stress" hemorrhage. Because of the relationship between liver function and the cause of hemorrhage, mortality was lower in variceal bleeders (29 p.cent) than in patients with spontaneous ulcerations (83 p.cent). In patients with severely impaired liver function, portacaval shunt was rarely indicated since hemorrhage was generally due to acute mucosal ulcerations. SN - 0301-1518 UR - https://www.unboundmedicine.com/medline/citation/1083014/[Digestive_tract_hemorrhages_of_cirrhotic_patients__Relation_between_hepatic_insufficiency_and_the_hemorrhagic_lesion]_ DB - PRIME DP - Unbound Medicine ER -