Tags

Type your tag names separated by a space and hit enter

Fraction of prostate cancer incidence attributed to diet in Athens, Greece.
Eur J Cancer Prev 2000; 9(2):119-23EJ

Abstract

Diet appears to be a major determinant in the incidence of prostate cancer. In a case-control study conducted in Athens, Greece, we found that dairy products, butter and seed oils were positively associated with risk of prostate cancer, whereas cooked and raw tomatoes were inversely associated. We utilized the data from this study to calculate the population attributable fractions under alternative assumptions of feasible dietary changes. For each subject, a dietary score was calculated and categorized into approximately quintiles, representing increasing levels of prostate cancer risk as a function of the intake of the five discriminatory food groups or items. Population attributable fractions in terms of this dietary score were calculated taking into account multivariate adjustment. We observed that, if all individuals were shifted to the baseline category, the incidence of prostate cancer in this study population would be reduced by 41% (95% confidence interval 23-59%). However, if all individuals were shifted to the adjacent lower risk quintile, the expected incidence reduction would be a more modest 19%. The incidence of prostate cancer in Greece could be reduced by about two-fifths if the population increased the consumption of tomatoes and reduced the intake of dairy products, and substituted olive oil for other added lipids.

Authors+Show Affiliations

Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy. bosetti@irfmn.mnegri.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10830579

Citation

Bosetti, C, et al. "Fraction of Prostate Cancer Incidence Attributed to Diet in Athens, Greece." European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), vol. 9, no. 2, 2000, pp. 119-23.
Bosetti C, Tzonou A, Lagiou P, et al. Fraction of prostate cancer incidence attributed to diet in Athens, Greece. Eur J Cancer Prev. 2000;9(2):119-23.
Bosetti, C., Tzonou, A., Lagiou, P., Negri, E., Trichopoulos, D., & Hsieh, C. C. (2000). Fraction of prostate cancer incidence attributed to diet in Athens, Greece. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), 9(2), pp. 119-23.
Bosetti C, et al. Fraction of Prostate Cancer Incidence Attributed to Diet in Athens, Greece. Eur J Cancer Prev. 2000;9(2):119-23. PubMed PMID: 10830579.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fraction of prostate cancer incidence attributed to diet in Athens, Greece. AU - Bosetti,C, AU - Tzonou,A, AU - Lagiou,P, AU - Negri,E, AU - Trichopoulos,D, AU - Hsieh,C C, PY - 2000/6/1/pubmed PY - 2000/9/23/medline PY - 2000/6/1/entrez SP - 119 EP - 23 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) JO - Eur. J. Cancer Prev. VL - 9 IS - 2 N2 - Diet appears to be a major determinant in the incidence of prostate cancer. In a case-control study conducted in Athens, Greece, we found that dairy products, butter and seed oils were positively associated with risk of prostate cancer, whereas cooked and raw tomatoes were inversely associated. We utilized the data from this study to calculate the population attributable fractions under alternative assumptions of feasible dietary changes. For each subject, a dietary score was calculated and categorized into approximately quintiles, representing increasing levels of prostate cancer risk as a function of the intake of the five discriminatory food groups or items. Population attributable fractions in terms of this dietary score were calculated taking into account multivariate adjustment. We observed that, if all individuals were shifted to the baseline category, the incidence of prostate cancer in this study population would be reduced by 41% (95% confidence interval 23-59%). However, if all individuals were shifted to the adjacent lower risk quintile, the expected incidence reduction would be a more modest 19%. The incidence of prostate cancer in Greece could be reduced by about two-fifths if the population increased the consumption of tomatoes and reduced the intake of dairy products, and substituted olive oil for other added lipids. SN - 0959-8278 UR - https://www.unboundmedicine.com/medline/citation/10830579/Fraction_of_prostate_cancer_incidence_attributed_to_diet_in_Athens_Greece_ L2 - http://Insights.ovid.com/pubmed?pmid=10830579 DB - PRIME DP - Unbound Medicine ER -