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Fine needle aspiration cytology in extramedullary plasmacytoma.
Acta Cytol. 2000 May-Jun; 44(3):287-91.AC

Abstract

OBJECTIVE

Extramedullary plasmacytoma is a rare plasma cell neoplasm. It can occur as the sole manifestation of plasma cell neoplasm, as a metastasis from another extramedullary plasmacytoma, as a solitary plasmacytoma of the bone or as a consequence of multiple myeloma. These plasma cell tumors can occur anywhere and have to be differentiated from other neoplasms, infectious processes and chloroma.

STUDY DESIGN

We report the findings of fine needle aspiration cytology (FNAC) in 18 patients with extramedullary plasmacytoma. In six patients extramedullary plasmacytoma was the initial presentation of plasma cell neoplasm. In the remaining 12 patients the tumors occurred under or after treatment of plasma cell disease.

RESULTS

Eleven lesions were located in the skin, seven in the lymph nodes, one in the liver and another in the spleen. Two patients with known diagnoses of plasma cell disease were thought, before FNAC, to have an infection, and two had a histologic diagnosis of non-Hodgkin's lymphoma. In 13 of 18 patients, cytologic smears showed anaplastic plasma cells.

CONCLUSION

FNAC is a front-line investigative procedure in diagnosing extramedullary plasmacytoma.

Authors+Show Affiliations

Department of Medicine III (Hematology, Oncology, Clinical Immunology and Infectious Disease), University of Ulm, Germany. markus.bangerter@medizin.uni-ulm.deNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10833979

Citation

Bangerter, M, et al. "Fine Needle Aspiration Cytology in Extramedullary Plasmacytoma." Acta Cytologica, vol. 44, no. 3, 2000, pp. 287-91.
Bangerter M, Hildebrand A, Waidmann O, et al. Fine needle aspiration cytology in extramedullary plasmacytoma. Acta Cytol. 2000;44(3):287-91.
Bangerter, M., Hildebrand, A., Waidmann, O., & Griesshammer, M. (2000). Fine needle aspiration cytology in extramedullary plasmacytoma. Acta Cytologica, 44(3), 287-91.
Bangerter M, et al. Fine Needle Aspiration Cytology in Extramedullary Plasmacytoma. Acta Cytol. 2000 May-Jun;44(3):287-91. PubMed PMID: 10833979.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fine needle aspiration cytology in extramedullary plasmacytoma. AU - Bangerter,M, AU - Hildebrand,A, AU - Waidmann,O, AU - Griesshammer,M, PY - 2000/6/2/pubmed PY - 2000/7/6/medline PY - 2000/6/2/entrez SP - 287 EP - 91 JF - Acta cytologica JO - Acta Cytol VL - 44 IS - 3 N2 - OBJECTIVE: Extramedullary plasmacytoma is a rare plasma cell neoplasm. It can occur as the sole manifestation of plasma cell neoplasm, as a metastasis from another extramedullary plasmacytoma, as a solitary plasmacytoma of the bone or as a consequence of multiple myeloma. These plasma cell tumors can occur anywhere and have to be differentiated from other neoplasms, infectious processes and chloroma. STUDY DESIGN: We report the findings of fine needle aspiration cytology (FNAC) in 18 patients with extramedullary plasmacytoma. In six patients extramedullary plasmacytoma was the initial presentation of plasma cell neoplasm. In the remaining 12 patients the tumors occurred under or after treatment of plasma cell disease. RESULTS: Eleven lesions were located in the skin, seven in the lymph nodes, one in the liver and another in the spleen. Two patients with known diagnoses of plasma cell disease were thought, before FNAC, to have an infection, and two had a histologic diagnosis of non-Hodgkin's lymphoma. In 13 of 18 patients, cytologic smears showed anaplastic plasma cells. CONCLUSION: FNAC is a front-line investigative procedure in diagnosing extramedullary plasmacytoma. SN - 0001-5547 UR - https://www.unboundmedicine.com/medline/citation/10833979/Fine_needle_aspiration_cytology_in_extramedullary_plasmacytoma_ L2 - https://www.karger.com?DOI=10.1159/000328466 DB - PRIME DP - Unbound Medicine ER -