Tags

Type your tag names separated by a space and hit enter

[Locally recurring extramedullary plasmacytoma of the upper aerodigestive tract].
Laryngorhinootologie. 2000 Apr; 79(4):213-20.L

Abstract

BACKGROUND

Extramedullary plasmacytomas (EMP) are plasma cell tumors in which by definition the primary tumor is extramedullary. Most of them are found in the upper aerodigestive tract.

PATIENTS

In this study we describe 3 patients with EMP. The first case is a locally recurrent EMP with recurrent involvement of cervical lymph nodes. The first manifestation of EMP was 31 years ago. Hence, this is one of the longest clinical courses of recurrent EMP ever described in the literature. Case 2 is a locally aggressive recurrent EMP. Case 3 is a localized solitary EMP that could be successfully treated by surgery alone.

RESULTS AND CONCLUSIONS

Different classifications of EMP described in the literature are discussed. If these classifications are applied to our cases neither the tumor stage nor the histological picture allow definite conclusions about the prognoses to be drawn. Metastases in regional lymph nodes do not necessarily mean a worse prognosis. Overall, compared to MM with a ten year survival rate of 18% the prognosis is more favorable in EMP with a ten year survival rate of 50%. After a generalized plasma cell neoplasia has been excluded EMP in the head and neck should be treated like a locally aggressive and potentially metastatic tumor. From our experiences we recommend a primary surgical therapy followed by radiation therapy if necessary.

Authors+Show Affiliations

Universitäts-HNO-Klinik Tübingen. ingo.baumann@t-online.deNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Comparative Study
English Abstract
Journal Article

Language

ger

PubMed ID

10838685

Citation

Baumann, I, et al. "[Locally Recurring Extramedullary Plasmacytoma of the Upper Aerodigestive Tract]." Laryngo- Rhino- Otologie, vol. 79, no. 4, 2000, pp. 213-20.
Baumann I, Ruck P, Dammann F, et al. [Locally recurring extramedullary plasmacytoma of the upper aerodigestive tract]. Laryngorhinootologie. 2000;79(4):213-20.
Baumann, I., Ruck, P., Dammann, F., & Plinkert, P. K. (2000). [Locally recurring extramedullary plasmacytoma of the upper aerodigestive tract]. Laryngo- Rhino- Otologie, 79(4), 213-20.
Baumann I, et al. [Locally Recurring Extramedullary Plasmacytoma of the Upper Aerodigestive Tract]. Laryngorhinootologie. 2000;79(4):213-20. PubMed PMID: 10838685.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Locally recurring extramedullary plasmacytoma of the upper aerodigestive tract]. AU - Baumann,I, AU - Ruck,P, AU - Dammann,F, AU - Plinkert,P K, PY - 2000/6/6/pubmed PY - 2000/7/6/medline PY - 2000/6/6/entrez SP - 213 EP - 20 JF - Laryngo- rhino- otologie JO - Laryngorhinootologie VL - 79 IS - 4 N2 - BACKGROUND: Extramedullary plasmacytomas (EMP) are plasma cell tumors in which by definition the primary tumor is extramedullary. Most of them are found in the upper aerodigestive tract. PATIENTS: In this study we describe 3 patients with EMP. The first case is a locally recurrent EMP with recurrent involvement of cervical lymph nodes. The first manifestation of EMP was 31 years ago. Hence, this is one of the longest clinical courses of recurrent EMP ever described in the literature. Case 2 is a locally aggressive recurrent EMP. Case 3 is a localized solitary EMP that could be successfully treated by surgery alone. RESULTS AND CONCLUSIONS: Different classifications of EMP described in the literature are discussed. If these classifications are applied to our cases neither the tumor stage nor the histological picture allow definite conclusions about the prognoses to be drawn. Metastases in regional lymph nodes do not necessarily mean a worse prognosis. Overall, compared to MM with a ten year survival rate of 18% the prognosis is more favorable in EMP with a ten year survival rate of 50%. After a generalized plasma cell neoplasia has been excluded EMP in the head and neck should be treated like a locally aggressive and potentially metastatic tumor. From our experiences we recommend a primary surgical therapy followed by radiation therapy if necessary. SN - 0935-8943 UR - https://www.unboundmedicine.com/medline/citation/10838685/[Locally_recurring_extramedullary_plasmacytoma_of_the_upper_aerodigestive_tract]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-8800 DB - PRIME DP - Unbound Medicine ER -