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Immunization of pediatric solid organ transplant candidates and recipients.
Clin Infect Dis. 2000 Jun; 30(6):857-69.CI

Abstract

Organ transplantation has evolved from an experimental procedure to an accepted treatment for otherwise irreversible or congenital disorders. The immunosuppression necessary to prevent rejection enhances the severity of many infectious diseases and may potentially attenuate the response to vaccines designed to prevent disease. In spite of the frequency and severity of infectious diseases in organ transplant recipients, many children are not fully vaccinated before transplantation. The safety and efficacy of many of the currently available vaccines for solid organ transplant recipients have not been evaluated. We review the currently available data on immunization safety and efficacy, discuss experimental vaccines, and outline strategies to avoid vaccine-preventable diseases in pediatric organ transplant recipients.

Authors+Show Affiliations

Department of Pediatrics, Division of Pediatric Infectious Diseases, Recanati-Miller Transplant Institute, Mount Sinai School of Medicine, New York, NY 10029, USA. peggy.burroughs@mssm.eduNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

10852737

Citation

Burroughs, M, and A Moscona. "Immunization of Pediatric Solid Organ Transplant Candidates and Recipients." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 30, no. 6, 2000, pp. 857-69.
Burroughs M, Moscona A. Immunization of pediatric solid organ transplant candidates and recipients. Clin Infect Dis. 2000;30(6):857-69.
Burroughs, M., & Moscona, A. (2000). Immunization of pediatric solid organ transplant candidates and recipients. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 30(6), 857-69.
Burroughs M, Moscona A. Immunization of Pediatric Solid Organ Transplant Candidates and Recipients. Clin Infect Dis. 2000;30(6):857-69. PubMed PMID: 10852737.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immunization of pediatric solid organ transplant candidates and recipients. AU - Burroughs,M, AU - Moscona,A, Y1 - 2000/06/13/ PY - 1999/08/06/received PY - 1999/11/17/revised PY - 2000/6/14/pubmed PY - 2000/9/19/medline PY - 2000/6/14/entrez SP - 857 EP - 69 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 30 IS - 6 N2 - Organ transplantation has evolved from an experimental procedure to an accepted treatment for otherwise irreversible or congenital disorders. The immunosuppression necessary to prevent rejection enhances the severity of many infectious diseases and may potentially attenuate the response to vaccines designed to prevent disease. In spite of the frequency and severity of infectious diseases in organ transplant recipients, many children are not fully vaccinated before transplantation. The safety and efficacy of many of the currently available vaccines for solid organ transplant recipients have not been evaluated. We review the currently available data on immunization safety and efficacy, discuss experimental vaccines, and outline strategies to avoid vaccine-preventable diseases in pediatric organ transplant recipients. SN - 1058-4838 UR - https://www.unboundmedicine.com/medline/citation/10852737/Immunization_of_pediatric_solid_organ_transplant_candidates_and_recipients_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/313823 DB - PRIME DP - Unbound Medicine ER -