TY - JOUR T1 - The comparison of toluene determination between headspace-solid phase microextraction and headspace methods in glue-sniffer's blood and urine samples. AU - Kim,N Y, AU - Park,S W, PY - 2000/6/16/pubmed PY - 2000/7/15/medline PY - 2000/6/16/entrez SP - 702 EP - 7 JF - Journal of forensic sciences JO - J Forensic Sci VL - 45 IS - 3 N2 - An accurate and simple method was developed to determine the level of toluene in urine and blood quantitatively by using the gas chromatography/mass spectrometry (GC/MS) with headspace--solid phase microextraction (HS-SPME) technique. An assembly of SPME with a replaceable extraction fiber, coated with 100 microm polydimethylsiloxane, was used. The detection limit of toluene in blood and urine with HS-SPME technique was 10 times higher than that with headspace (HS) technique. To compare the HS-SPME with HS technique for the determination of toluene in biological fluids, blood and urine samples from glue sniffers were analyzed by both methods. The level of toluene by the two techniques was highly correlated: the correlation coefficient (r2) between the two sets of values were 0.98 and 0.96 in urine and blood, respectively. SN - 0022-1198 UR - https://www.unboundmedicine.com/medline/citation/10855984/The_comparison_of_toluene_determination_between_headspace_solid_phase_microextraction_and_headspace_methods_in_glue_sniffer's_blood_and_urine_samples_ L2 - https://medlineplus.gov/druguseandaddiction.html DB - PRIME DP - Unbound Medicine ER -