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Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls.
Eur J Clin Nutr 2000; 54(6):514-21EJ

Abstract

OBJECTIVE

Malnutrition is observed frequently in patients with inflammatory bowel disease (IBD). Knowledge of the nutritional status in patients with recently diagnosed IBD is limited. The aim of this study was to establish a comprehensive picture of the nutritional status in recently diagnosed IBD patients.

SUBJECTS

Sixty-nine IBD patients (23 Crohn's disease (CD) and 46 with ulcerative colitis (UC)) within 6 months of diagnosis and 69 age- and sex-matched population controls were included in the study.

METHODS

The nutritional status was assessed by: (1) body composition (anthropometry and dual-energy X-ray absorptiometry); (2) dietary intake (dietary history); (3) biochemical indexes of nutrition; and (4) muscle strength (isokinetic dynamometer).

RESULTS

Body weight and body mass index were significantly lower in UC patients compared with controls. The mean daily intake of carbohydrates was significantly higher in CD patients and the intakes of protein, calcium, phosphorus, and riboflavin were significantly lower in UC patients compared with controls, respectively. Serum concentrations of several nutrients (beta-carotene, magnesium, selenium and zinc) were significantly lower in UC patients compared with controls. Serum vitamin B12 concentration was significantly lower in CD patients. Muscle strength did not significantly differ between IBD patients and controls.

CONCLUSIONS

This study showed that the nutritional status of IBD patients was already affected negatively at time of diagnosis. It needs to be elucidated whether nutritional supplementation in recently diagnosed IBD patients may improve the clinical course of the disease.

Authors+Show Affiliations

Department of Gastroenterology, University Hospital Maastricht, The Netherlands.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10878655

Citation

Geerling, B J., et al. "Comprehensive Nutritional Status in Recently Diagnosed Patients With Inflammatory Bowel Disease Compared With Population Controls." European Journal of Clinical Nutrition, vol. 54, no. 6, 2000, pp. 514-21.
Geerling BJ, Badart-Smook A, Stockbrügger RW, et al. Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls. Eur J Clin Nutr. 2000;54(6):514-21.
Geerling, B. J., Badart-Smook, A., Stockbrügger, R. W., & Brummer, R. J. (2000). Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls. European Journal of Clinical Nutrition, 54(6), pp. 514-21.
Geerling BJ, et al. Comprehensive Nutritional Status in Recently Diagnosed Patients With Inflammatory Bowel Disease Compared With Population Controls. Eur J Clin Nutr. 2000;54(6):514-21. PubMed PMID: 10878655.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls. AU - Geerling,B J, AU - Badart-Smook,A, AU - Stockbrügger,R W, AU - Brummer,R J, PY - 2000/7/6/pubmed PY - 2000/8/6/medline PY - 2000/7/6/entrez SP - 514 EP - 21 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 54 IS - 6 N2 - OBJECTIVE: Malnutrition is observed frequently in patients with inflammatory bowel disease (IBD). Knowledge of the nutritional status in patients with recently diagnosed IBD is limited. The aim of this study was to establish a comprehensive picture of the nutritional status in recently diagnosed IBD patients. SUBJECTS: Sixty-nine IBD patients (23 Crohn's disease (CD) and 46 with ulcerative colitis (UC)) within 6 months of diagnosis and 69 age- and sex-matched population controls were included in the study. METHODS: The nutritional status was assessed by: (1) body composition (anthropometry and dual-energy X-ray absorptiometry); (2) dietary intake (dietary history); (3) biochemical indexes of nutrition; and (4) muscle strength (isokinetic dynamometer). RESULTS: Body weight and body mass index were significantly lower in UC patients compared with controls. The mean daily intake of carbohydrates was significantly higher in CD patients and the intakes of protein, calcium, phosphorus, and riboflavin were significantly lower in UC patients compared with controls, respectively. Serum concentrations of several nutrients (beta-carotene, magnesium, selenium and zinc) were significantly lower in UC patients compared with controls. Serum vitamin B12 concentration was significantly lower in CD patients. Muscle strength did not significantly differ between IBD patients and controls. CONCLUSIONS: This study showed that the nutritional status of IBD patients was already affected negatively at time of diagnosis. It needs to be elucidated whether nutritional supplementation in recently diagnosed IBD patients may improve the clinical course of the disease. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/10878655/Comprehensive_nutritional_status_in_recently_diagnosed_patients_with_inflammatory_bowel_disease_compared_with_population_controls_ L2 - https://medlineplus.gov/crohnsdisease.html DB - PRIME DP - Unbound Medicine ER -