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Ferritin and serum iron levels in adult patients with sickle cell anaemia at Ibadan, Nigeria.
Afr J Med Med Sci 1997 Mar-Jun; 26(1-2):39-41AJ

Abstract

The ferritin and serum iron levels in 100 adult patients with sickle cell anaemia (SCA) and in ten pregnant (SCA) females were measured. All the adult sickle cell anaemia patients had serum ferritin levels ranging between 325 ng/dl and > 1500 ng/dl. These levels are within and above the normal range. The same trend was observed in the pregnant adult females with SCA. However, in the pregnant women, significantly lower ferritin levels than in the non-pregnant women were recorded. There is, therefore, a reduction in ferritin levels in pregnancy. This could be due to the increased iron requirements and demand by the developing foetus. Serum iron was below normal in 30% of the pregnant women, only 6% of all the adult patients had serum iron levels below the normal levels. Given the adequacy of ferritin levels in the patients studied and the very low incidence of below normal serum iron levels, it is concluded that the sickle cell anaemia patients in the area of study have adequate levels of iron and ferritin in their serum. Iron should therefore be given only in proven cases of iron deficiency anaemia.

Authors+Show Affiliations

Department of Haematology, College of Medicine, University of Ibadan.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10895227

Citation

Aken'Ova, Y A., et al. "Ferritin and Serum Iron Levels in Adult Patients With Sickle Cell Anaemia at Ibadan, Nigeria." African Journal of Medicine and Medical Sciences, vol. 26, no. 1-2, 1997, pp. 39-41.
Aken'Ova YA, Adeyefa I, Okunade M. Ferritin and serum iron levels in adult patients with sickle cell anaemia at Ibadan, Nigeria. Afr J Med Med Sci. 1997;26(1-2):39-41.
Aken'Ova, Y. A., Adeyefa, I., & Okunade, M. (1997). Ferritin and serum iron levels in adult patients with sickle cell anaemia at Ibadan, Nigeria. African Journal of Medicine and Medical Sciences, 26(1-2), pp. 39-41.
Aken'Ova YA, Adeyefa I, Okunade M. Ferritin and Serum Iron Levels in Adult Patients With Sickle Cell Anaemia at Ibadan, Nigeria. Afr J Med Med Sci. 1997;26(1-2):39-41. PubMed PMID: 10895227.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ferritin and serum iron levels in adult patients with sickle cell anaemia at Ibadan, Nigeria. AU - Aken'Ova,Y A, AU - Adeyefa,I, AU - Okunade,M, PY - 1997/3/1/pubmed PY - 2000/8/12/medline PY - 1997/3/1/entrez SP - 39 EP - 41 JF - African journal of medicine and medical sciences JO - Afr J Med Med Sci VL - 26 IS - 1-2 N2 - The ferritin and serum iron levels in 100 adult patients with sickle cell anaemia (SCA) and in ten pregnant (SCA) females were measured. All the adult sickle cell anaemia patients had serum ferritin levels ranging between 325 ng/dl and > 1500 ng/dl. These levels are within and above the normal range. The same trend was observed in the pregnant adult females with SCA. However, in the pregnant women, significantly lower ferritin levels than in the non-pregnant women were recorded. There is, therefore, a reduction in ferritin levels in pregnancy. This could be due to the increased iron requirements and demand by the developing foetus. Serum iron was below normal in 30% of the pregnant women, only 6% of all the adult patients had serum iron levels below the normal levels. Given the adequacy of ferritin levels in the patients studied and the very low incidence of below normal serum iron levels, it is concluded that the sickle cell anaemia patients in the area of study have adequate levels of iron and ferritin in their serum. Iron should therefore be given only in proven cases of iron deficiency anaemia. SN - 0309-3913 UR - https://www.unboundmedicine.com/medline/citation/10895227/Ferritin_and_serum_iron_levels_in_adult_patients_with_sickle_cell_anaemia_at_Ibadan_Nigeria_ L2 - https://medlineplus.gov/iron.html DB - PRIME DP - Unbound Medicine ER -