Tags

Type your tag names separated by a space and hit enter

Lung cancer in New South Wales: current trends and the influence of age and sex.
Med J Aust 2000; 172(12):578-82MJ

Abstract

OBJECTIVE

To examine the effects of time, sex and age at diagnosis on lung cancer incidence rates and the distribution of the histological types of lung cancer in New South Wales.

DESIGN AND SETTING

Retrospective analysis of data from the NSW Cancer Registry and Australian Bureau of Statistics population data for NSW for 1985-1995.

MAIN OUTCOME MEASURES

Trends in lung cancer incidence rates between 1985 and 1995 for men and women aged over 30 years; changes in incidence rates within age groups; and incidence rates of histological subtypes relative to sex and age.

RESULTS

The incidence of lung cancer in men aged 40-80 years fell, while that in women aged over 65 rose. Rates were stable in younger women and older men. Incidence rates in men aged 40-60 years fell by 40%-60%. Were it not for the reduction in incidence rates in men between 1985 and 1995, the number of male lung cancer cases in 1995 would have been greater by 389 (95% CI, 362-415). In women, increasing incidence rates were responsible for an extra 242 cases (95% CI, 232-253) in 1995. Adenocarcinoma comprised a greater percentage of lung cancer cases in younger people, while squamous-cell carcinoma increases steadily with age in both men and women. Women with lung cancer are less likely to have squamous-cell carcinoma (25% for women v. 40% for men) and therefore more likely than men to have adenocarcinoma (35% of new female cases v. 26% for men) or small-cell lung cancer (24% v. 19%).

CONCLUSIONS

Increased smoking cessation has seen a halving of lung cancer rates in middle-aged men. Whether this represents delayed or prevented cases is uncertain. The distribution of histological subtypes of lung cancer in women is different from that in men, and it is not clear whether this difference is hormone-dependent or related to historical patterns of smoking.

Authors+Show Affiliations

Department of Thoracic Medicine, Concord Repatriation General Hospital, Concord, NSW.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10914102

Citation

Morgan, L C., et al. "Lung Cancer in New South Wales: Current Trends and the Influence of Age and Sex." The Medical Journal of Australia, vol. 172, no. 12, 2000, pp. 578-82.
Morgan LC, Grayson D, Peters HE, et al. Lung cancer in New South Wales: current trends and the influence of age and sex. Med J Aust. 2000;172(12):578-82.
Morgan, L. C., Grayson, D., Peters, H. E., Clarke, C. W., & Peters, M. J. (2000). Lung cancer in New South Wales: current trends and the influence of age and sex. The Medical Journal of Australia, 172(12), pp. 578-82.
Morgan LC, et al. Lung Cancer in New South Wales: Current Trends and the Influence of Age and Sex. Med J Aust. 2000 Jun 19;172(12):578-82. PubMed PMID: 10914102.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lung cancer in New South Wales: current trends and the influence of age and sex. AU - Morgan,L C, AU - Grayson,D, AU - Peters,H E, AU - Clarke,C W, AU - Peters,M J, PY - 2000/7/29/pubmed PY - 2000/8/19/medline PY - 2000/7/29/entrez SP - 578 EP - 82 JF - The Medical journal of Australia JO - Med. J. Aust. VL - 172 IS - 12 N2 - OBJECTIVE: To examine the effects of time, sex and age at diagnosis on lung cancer incidence rates and the distribution of the histological types of lung cancer in New South Wales. DESIGN AND SETTING: Retrospective analysis of data from the NSW Cancer Registry and Australian Bureau of Statistics population data for NSW for 1985-1995. MAIN OUTCOME MEASURES: Trends in lung cancer incidence rates between 1985 and 1995 for men and women aged over 30 years; changes in incidence rates within age groups; and incidence rates of histological subtypes relative to sex and age. RESULTS: The incidence of lung cancer in men aged 40-80 years fell, while that in women aged over 65 rose. Rates were stable in younger women and older men. Incidence rates in men aged 40-60 years fell by 40%-60%. Were it not for the reduction in incidence rates in men between 1985 and 1995, the number of male lung cancer cases in 1995 would have been greater by 389 (95% CI, 362-415). In women, increasing incidence rates were responsible for an extra 242 cases (95% CI, 232-253) in 1995. Adenocarcinoma comprised a greater percentage of lung cancer cases in younger people, while squamous-cell carcinoma increases steadily with age in both men and women. Women with lung cancer are less likely to have squamous-cell carcinoma (25% for women v. 40% for men) and therefore more likely than men to have adenocarcinoma (35% of new female cases v. 26% for men) or small-cell lung cancer (24% v. 19%). CONCLUSIONS: Increased smoking cessation has seen a halving of lung cancer rates in middle-aged men. Whether this represents delayed or prevented cases is uncertain. The distribution of histological subtypes of lung cancer in women is different from that in men, and it is not clear whether this difference is hormone-dependent or related to historical patterns of smoking. SN - 0025-729X UR - https://www.unboundmedicine.com/medline/citation/10914102/Lung_cancer_in_New_South_Wales:_current_trends_and_the_influence_of_age_and_sex_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0025-729X&date=2000&volume=172&issue=12&spage=578 DB - PRIME DP - Unbound Medicine ER -